MiR‐24 enhances radiosensitivity in nasopharyngeal carcinoma by targeting SP1

Radioresistance remains a major problem in the treatment of patients suffering from nasopharyngeal carcinoma (NPC). A better understanding of the mechanisms of radioresistance may generate new strategies to improve NPC patients' responses to therapy. This study was designed to investigate the e...

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Veröffentlicht in:	Cancer medicine (Malden, MA) MA), 2016-06, Vol.5 (6), p.1163-1173
Hauptverfasser:	Kang, Min, Xiao, Jingjian, Wang, Jun, Zhou, Pingting, Wei, Tingting, Zhao, Tingting, Wang, Rensheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Cancer Biology Carcinoma Cell Line, Tumor Cell Survival - genetics Cell Survival - radiation effects Disease Models, Animal Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Male Mice MicroRNAs - chemistry MicroRNAs - genetics Middle Aged miR‐24 Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - pathology Nasopharyngeal Neoplasms - radiotherapy Original Research Radiation Tolerance - genetics radiosensitivity RNA Interference RNA, Messenger - chemistry RNA, Messenger - genetics SP1 Sp1 Transcription Factor - genetics Xenograft Model Antitumor Assays Young Adult
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