Cutaneous afferent activity in median and radial nerve fascicles: a microelectrode study
Cutaneous afferent activity was recorded in fascicles of the median and radial nerves of normal subjects using percutaneous microelectrodes. Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and...
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| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1975-09, Vol.38 (9), p.855-864 |
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| container_end_page | 864 |
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| container_issue | 9 |
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| container_title | Journal of neurology, neurosurgery and psychiatry |
| container_volume | 38 |
| creator | Burke, D Mackenzie, R A Skuse, N F Lethlean, A K |
| description | Cutaneous afferent activity was recorded in fascicles of the median and radial nerves of normal subjects using percutaneous microelectrodes. Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and slow myelinated fibre activity but more intense levels were required to activate unmyelinated fibres. Correlation of the evoked potentials and the sensations reported by the subject suggested that fast myelinated fibres mediate tactile sensations. Pricking pain appeared with the activation of slow myelinated fibres. The only sensations induced by electrical stimuli were tactile or painful. |
| doi_str_mv | 10.1136/jnnp.38.9.855 |
| format | Article |
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Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and slow myelinated fibre activity but more intense levels were required to activate unmyelinated fibres. Correlation of the evoked potentials and the sensations reported by the subject suggested that fast myelinated fibres mediate tactile sensations. Pricking pain appeared with the activation of slow myelinated fibres. The only sensations induced by electrical stimuli were tactile or painful.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.38.9.855</identifier><identifier>PMID: 1185224</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Adult ; Electric Stimulation ; Evoked Potentials ; Humans ; Median Nerve - physiology ; Middle Aged ; Nerve Fibers, Myelinated - physiology ; Neurons, Afferent - physiology ; Pain ; Radial Nerve - physiology ; Skin - innervation ; Touch - physiology</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 1975-09, Vol.38 (9), p.855-864</ispartof><rights>Copyright BMJ Publishing Group LTD Sep 1975</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b480t-2b996b5273fc781250b4b3217dadbe4b817069619e4c9cfff844acdda0e1608d3</citedby><cites>FETCH-LOGICAL-b480t-2b996b5273fc781250b4b3217dadbe4b817069619e4c9cfff844acdda0e1608d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC492114/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC492114/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1185224$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burke, D</creatorcontrib><creatorcontrib>Mackenzie, R A</creatorcontrib><creatorcontrib>Skuse, N F</creatorcontrib><creatorcontrib>Lethlean, A K</creatorcontrib><title>Cutaneous afferent activity in median and radial nerve fascicles: a microelectrode study</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>Cutaneous afferent activity was recorded in fascicles of the median and radial nerves of normal subjects using percutaneous microelectrodes. Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and slow myelinated fibre activity but more intense levels were required to activate unmyelinated fibres. Correlation of the evoked potentials and the sensations reported by the subject suggested that fast myelinated fibres mediate tactile sensations. Pricking pain appeared with the activation of slow myelinated fibres. The only sensations induced by electrical stimuli were tactile or painful.</description><subject>Adult</subject><subject>Electric Stimulation</subject><subject>Evoked Potentials</subject><subject>Humans</subject><subject>Median Nerve - physiology</subject><subject>Middle Aged</subject><subject>Nerve Fibers, Myelinated - physiology</subject><subject>Neurons, Afferent - physiology</subject><subject>Pain</subject><subject>Radial Nerve - physiology</subject><subject>Skin - innervation</subject><subject>Touch - physiology</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1v1DAQhi1EVbaFI0ckS0iolyz-TGykHtAKaGFFL4X2ZtmOA14SZ7GdFfvv8SpVC1yYi0eaZ8bvzAvAc4yWGNP69SaE7ZKKpVwKzh-BBWa1qChFt4_BAiFCKoo4egJOUtqgQwh5DI4xFpwQtgC3qynr4MYpQd11LrqQobbZ73zeQx_g4FqvA9ShhVGXtIfBxZ2DnU7W296lN1DDwds4ut7ZHMfWwZSndv8UHHW6T-7Z3XsKvrx_d726qNZXHy5Xb9eVYQLlihgpa8NJQzvbCEw4MsxQgptWt8YxI3CDallj6ZiVtus6wZi2bauRwzUSLT0F5_Pc7WSKWFsWiLpX2-gHHfdq1F79XQn-u_o27hSTBGNW-l_d9cfx5-RSVoNP1vX9fBUlKCISY1nAl_-Am3GKoeymcNMQgRDHTaGqmSoXSSm67l4JRurglzr4pahQUhW_Cv_iT_kP9GzQwzyfsvt1X9bxh6ob2nD1-etK8fVNfXPxSaqPhT-beTNs_vP1b0VDr3I</recordid><startdate>19750901</startdate><enddate>19750901</enddate><creator>Burke, D</creator><creator>Mackenzie, R A</creator><creator>Skuse, N F</creator><creator>Lethlean, A K</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19750901</creationdate><title>Cutaneous afferent activity in median and radial nerve fascicles: a microelectrode study</title><author>Burke, D ; 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Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and slow myelinated fibre activity but more intense levels were required to activate unmyelinated fibres. Correlation of the evoked potentials and the sensations reported by the subject suggested that fast myelinated fibres mediate tactile sensations. Pricking pain appeared with the activation of slow myelinated fibres. The only sensations induced by electrical stimuli were tactile or painful.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>1185224</pmid><doi>10.1136/jnnp.38.9.855</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of neurology, neurosurgery and psychiatry, 1975-09, Vol.38 (9), p.855-864 |
| issn | 0022-3050 1468-330X |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Electric Stimulation Evoked Potentials Humans Median Nerve - physiology Middle Aged Nerve Fibers, Myelinated - physiology Neurons, Afferent - physiology Pain Radial Nerve - physiology Skin - innervation Touch - physiology |
| title | Cutaneous afferent activity in median and radial nerve fascicles: a microelectrode study |
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