Docosahexaenoic Acid Modulates Invasion and Metastasis of Human Ovarian Cancer via Multiple Molecular Pathways

OBJECTIVEWe investigated the effect of docosahexaenoic acid (DHA) on the invasion and metastasis of ovarian cancer cells (A2780, HO8910, and SKOV-3). METHODSCytotoxicity assay was performed to determine the optimal doses of DHA in this experiment. The effects of DHA on invasion ability were assessed...

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Veröffentlicht in:	International journal of gynecological cancer 2016-07, Vol.26 (6), p.994-1003
Hauptverfasser:	Wang, Ying-Chun, Wu, Yi-Nan, Wang, Su-Li, Lin, Qing-Hua, He, Ming-Fang, Liu, Qiao-lin, Wang, Jin-Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Animals, Genetically Modified Basic Science Cell Line, Tumor Cell Survival - drug effects Docosahexaenoic Acids - pharmacology Down-Regulation - drug effects Female Humans Male Metastasis Neoplasm Invasiveness Neoplasm Metastasis Ovarian cancer Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology RNA, Messenger - biosynthesis RNA, Messenger - genetics Xenograft Model Antitumor Assays Zebrafish
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