Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus
Study Objective To determine whether a relationship exists between medication adherence to angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) and distance to dispensing pharmacies and prescribers among an urban public aid population with diabetes mellitus. D...
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| Veröffentlicht in: | Pharmacotherapy 2016-06, Vol.36 (6), p.590-597 |
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| container_title | Pharmacotherapy |
| container_volume | 36 |
| creator | Syed, Samina T. Sharp, Lisa K. Kim, Yoonsang Jentleson, Adam Lora, Claudia M. Touchette, Daniel R. Berbaum, Michael L. Suda, Katie J. Gerber, Ben S. |
| description | Study Objective
To determine whether a relationship exists between medication adherence to angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) and distance to dispensing pharmacies and prescribers among an urban public aid population with diabetes mellitus.
Design
Retrospective cohort study using claims data.
Data Source
Illinois Department of Healthcare and Family Services database.
Patients
A total of 6532 patients aged 18–64 years with diabetes who had at least one prescription fill for an ACEI or ARB and had continuous Medicaid coverage in the greater Chicago area in 2009.
Measurements and Main Results
We assessed medication adherence, defined as proportion of days covered (PDC) of 0.8 or higher, to ACEIs and ARBs and its association with distances between patients and their pharmacies and prescribers. Of the 6532 patients included in the analyses, 2930 (45%) had PDC levels of 0.8 or higher. No significant differences were observed between patients who were adherent versus those who were nonadherent in distance to pharmacy (median 1.39 vs 1.35 miles, p=0.15) or distance to prescriber (median 4.39 vs 4.48 miles, p=0.80). In a multivariate regression model including age, sex, race/ethnicity, number of pharmacies, number of prescribers, distance to pharmacy, and distance to prescriber, a greater number of prescribers was associated with higher adherence (two prescribers vs one prescriber: odds ratio [OR] 1.396, 95% confidence interval [CI] 1.233–1.580; three or more prescribers vs one prescriber: OR 2.208, 95% CI 1.787–2.727).
Conclusion
ACEI or ARB adherence was not associated with distances to pharmacies and prescribers. |
| doi_str_mv | 10.1002/phar.1757 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4919160</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1799562548</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5517-17a978427a4ee282dcf0c6ccf8229880200c91e81849d56aed2794de53ac8103</originalsourceid><addsrcrecordid>eNp1kd9u0zAUhy0EYt3gghdAkbiBi2y2E8f2DVJX1g1pg6oaAnFjuc7p6pE4wU4oexTeFmfpKkDiyv--8_kc_RB6QfAxwZietBvtjwln_BGaEMFZKgnJH6MJppynGGNxgA5DuI0oKXL6FB1QjgWnDE_QryVUurONCxvbJqfQbQFccgWlNffXybTcgAdnINGuTN7Z0Onh0DXDvgUXrLtJFrGBWhsL4Z5aeAjG2xX4kEzrJgLaJZ_8Sj-YbWSath9_Tra220SbXkEXBVdQVbbrwzP0ZK2rAM936xG6np9dzy7Sy4_n72fTy9QwRnhKuJZc5JTrHIAKWpo1NoUxa0GpFAJTjI0kIIjIZckKDSXlMi-BZdoIgrMj9HbUtv2qhtKA67yuVOttrf2darRVf784u1E3zQ-VSyJJMQhe7wS--d5D6FRtg4lDaAdNHxThUrKCslxE9NU_6G3TexenGyghmcgEjdSbkTK-CcHDet8MwWrIWw15qyHvyL78s_s9-RBwBE5GYGsruPu_SS0upsudMh0rYtTwc1-h_TdV8Iwz9fnDufoq58svfHaq5tlvS5THJQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1798958382</pqid></control><display><type>article</type><title>Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Syed, Samina T. ; Sharp, Lisa K. ; Kim, Yoonsang ; Jentleson, Adam ; Lora, Claudia M. ; Touchette, Daniel R. ; Berbaum, Michael L. ; Suda, Katie J. ; Gerber, Ben S.</creator><creatorcontrib>Syed, Samina T. ; Sharp, Lisa K. ; Kim, Yoonsang ; Jentleson, Adam ; Lora, Claudia M. ; Touchette, Daniel R. ; Berbaum, Michael L. ; Suda, Katie J. ; Gerber, Ben S.</creatorcontrib><description>Study Objective
To determine whether a relationship exists between medication adherence to angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) and distance to dispensing pharmacies and prescribers among an urban public aid population with diabetes mellitus.
Design
Retrospective cohort study using claims data.
Data Source
Illinois Department of Healthcare and Family Services database.
Patients
A total of 6532 patients aged 18–64 years with diabetes who had at least one prescription fill for an ACEI or ARB and had continuous Medicaid coverage in the greater Chicago area in 2009.
Measurements and Main Results
We assessed medication adherence, defined as proportion of days covered (PDC) of 0.8 or higher, to ACEIs and ARBs and its association with distances between patients and their pharmacies and prescribers. Of the 6532 patients included in the analyses, 2930 (45%) had PDC levels of 0.8 or higher. No significant differences were observed between patients who were adherent versus those who were nonadherent in distance to pharmacy (median 1.39 vs 1.35 miles, p=0.15) or distance to prescriber (median 4.39 vs 4.48 miles, p=0.80). In a multivariate regression model including age, sex, race/ethnicity, number of pharmacies, number of prescribers, distance to pharmacy, and distance to prescriber, a greater number of prescribers was associated with higher adherence (two prescribers vs one prescriber: odds ratio [OR] 1.396, 95% confidence interval [CI] 1.233–1.580; three or more prescribers vs one prescriber: OR 2.208, 95% CI 1.787–2.727).
Conclusion
ACEI or ARB adherence was not associated with distances to pharmacies and prescribers.</description><identifier>ISSN: 0277-0008</identifier><identifier>EISSN: 1875-9114</identifier><identifier>DOI: 10.1002/phar.1757</identifier><identifier>PMID: 27087250</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; angiotensin II receptor blocker ; Angiotensin Receptor Antagonists - therapeutic use ; angiotensin-converting enzyme inhibitor ; Angiotensin-Converting Enzyme Inhibitors - therapeutic use ; Confidence intervals ; Databases, Factual ; Diabetes ; diabetes mellitus ; Diabetes Mellitus - drug therapy ; Drug stores ; Female ; Geography, Medical - statistics & numerical data ; health services accessibility ; Humans ; Male ; medication adherence ; Medication Adherence - statistics & numerical data ; Middle Aged ; Pharmacies - statistics & numerical data ; Pharmacy ; Physicians - statistics & numerical data ; Retrospective Studies ; transportation ; Urban Population - statistics & numerical data ; Young Adult</subject><ispartof>Pharmacotherapy, 2016-06, Vol.36 (6), p.590-597</ispartof><rights>2016 Pharmacotherapy Publications, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5517-17a978427a4ee282dcf0c6ccf8229880200c91e81849d56aed2794de53ac8103</citedby><cites>FETCH-LOGICAL-c5517-17a978427a4ee282dcf0c6ccf8229880200c91e81849d56aed2794de53ac8103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fphar.1757$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fphar.1757$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27087250$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Syed, Samina T.</creatorcontrib><creatorcontrib>Sharp, Lisa K.</creatorcontrib><creatorcontrib>Kim, Yoonsang</creatorcontrib><creatorcontrib>Jentleson, Adam</creatorcontrib><creatorcontrib>Lora, Claudia M.</creatorcontrib><creatorcontrib>Touchette, Daniel R.</creatorcontrib><creatorcontrib>Berbaum, Michael L.</creatorcontrib><creatorcontrib>Suda, Katie J.</creatorcontrib><creatorcontrib>Gerber, Ben S.</creatorcontrib><title>Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus</title><title>Pharmacotherapy</title><addtitle>Pharmacotherapy</addtitle><description>Study Objective
To determine whether a relationship exists between medication adherence to angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) and distance to dispensing pharmacies and prescribers among an urban public aid population with diabetes mellitus.
Design
Retrospective cohort study using claims data.
Data Source
Illinois Department of Healthcare and Family Services database.
Patients
A total of 6532 patients aged 18–64 years with diabetes who had at least one prescription fill for an ACEI or ARB and had continuous Medicaid coverage in the greater Chicago area in 2009.
Measurements and Main Results
We assessed medication adherence, defined as proportion of days covered (PDC) of 0.8 or higher, to ACEIs and ARBs and its association with distances between patients and their pharmacies and prescribers. Of the 6532 patients included in the analyses, 2930 (45%) had PDC levels of 0.8 or higher. No significant differences were observed between patients who were adherent versus those who were nonadherent in distance to pharmacy (median 1.39 vs 1.35 miles, p=0.15) or distance to prescriber (median 4.39 vs 4.48 miles, p=0.80). In a multivariate regression model including age, sex, race/ethnicity, number of pharmacies, number of prescribers, distance to pharmacy, and distance to prescriber, a greater number of prescribers was associated with higher adherence (two prescribers vs one prescriber: odds ratio [OR] 1.396, 95% confidence interval [CI] 1.233–1.580; three or more prescribers vs one prescriber: OR 2.208, 95% CI 1.787–2.727).
Conclusion
ACEI or ARB adherence was not associated with distances to pharmacies and prescribers.</description><subject>Adolescent</subject><subject>Adult</subject><subject>angiotensin II receptor blocker</subject><subject>Angiotensin Receptor Antagonists - therapeutic use</subject><subject>angiotensin-converting enzyme inhibitor</subject><subject>Angiotensin-Converting Enzyme Inhibitors - therapeutic use</subject><subject>Confidence intervals</subject><subject>Databases, Factual</subject><subject>Diabetes</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus - drug therapy</subject><subject>Drug stores</subject><subject>Female</subject><subject>Geography, Medical - statistics & numerical data</subject><subject>health services accessibility</subject><subject>Humans</subject><subject>Male</subject><subject>medication adherence</subject><subject>Medication Adherence - statistics & numerical data</subject><subject>Middle Aged</subject><subject>Pharmacies - statistics & numerical data</subject><subject>Pharmacy</subject><subject>Physicians - statistics & numerical data</subject><subject>Retrospective Studies</subject><subject>transportation</subject><subject>Urban Population - statistics & numerical data</subject><subject>Young Adult</subject><issn>0277-0008</issn><issn>1875-9114</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kd9u0zAUhy0EYt3gghdAkbiBi2y2E8f2DVJX1g1pg6oaAnFjuc7p6pE4wU4oexTeFmfpKkDiyv--8_kc_RB6QfAxwZietBvtjwln_BGaEMFZKgnJH6MJppynGGNxgA5DuI0oKXL6FB1QjgWnDE_QryVUurONCxvbJqfQbQFccgWlNffXybTcgAdnINGuTN7Z0Onh0DXDvgUXrLtJFrGBWhsL4Z5aeAjG2xX4kEzrJgLaJZ_8Sj-YbWSath9_Tra220SbXkEXBVdQVbbrwzP0ZK2rAM936xG6np9dzy7Sy4_n72fTy9QwRnhKuJZc5JTrHIAKWpo1NoUxa0GpFAJTjI0kIIjIZckKDSXlMi-BZdoIgrMj9HbUtv2qhtKA67yuVOttrf2darRVf784u1E3zQ-VSyJJMQhe7wS--d5D6FRtg4lDaAdNHxThUrKCslxE9NU_6G3TexenGyghmcgEjdSbkTK-CcHDet8MwWrIWw15qyHvyL78s_s9-RBwBE5GYGsruPu_SS0upsudMh0rYtTwc1-h_TdV8Iwz9fnDufoq58svfHaq5tlvS5THJQ</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Syed, Samina T.</creator><creator>Sharp, Lisa K.</creator><creator>Kim, Yoonsang</creator><creator>Jentleson, Adam</creator><creator>Lora, Claudia M.</creator><creator>Touchette, Daniel R.</creator><creator>Berbaum, Michael L.</creator><creator>Suda, Katie J.</creator><creator>Gerber, Ben S.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201606</creationdate><title>Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus</title><author>Syed, Samina T. ; Sharp, Lisa K. ; Kim, Yoonsang ; Jentleson, Adam ; Lora, Claudia M. ; Touchette, Daniel R. ; Berbaum, Michael L. ; Suda, Katie J. ; Gerber, Ben S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5517-17a978427a4ee282dcf0c6ccf8229880200c91e81849d56aed2794de53ac8103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>angiotensin II receptor blocker</topic><topic>Angiotensin Receptor Antagonists - therapeutic use</topic><topic>angiotensin-converting enzyme inhibitor</topic><topic>Angiotensin-Converting Enzyme Inhibitors - therapeutic use</topic><topic>Confidence intervals</topic><topic>Databases, Factual</topic><topic>Diabetes</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus - drug therapy</topic><topic>Drug stores</topic><topic>Female</topic><topic>Geography, Medical - statistics & numerical data</topic><topic>health services accessibility</topic><topic>Humans</topic><topic>Male</topic><topic>medication adherence</topic><topic>Medication Adherence - statistics & numerical data</topic><topic>Middle Aged</topic><topic>Pharmacies - statistics & numerical data</topic><topic>Pharmacy</topic><topic>Physicians - statistics & numerical data</topic><topic>Retrospective Studies</topic><topic>transportation</topic><topic>Urban Population - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Syed, Samina T.</creatorcontrib><creatorcontrib>Sharp, Lisa K.</creatorcontrib><creatorcontrib>Kim, Yoonsang</creatorcontrib><creatorcontrib>Jentleson, Adam</creatorcontrib><creatorcontrib>Lora, Claudia M.</creatorcontrib><creatorcontrib>Touchette, Daniel R.</creatorcontrib><creatorcontrib>Berbaum, Michael L.</creatorcontrib><creatorcontrib>Suda, Katie J.</creatorcontrib><creatorcontrib>Gerber, Ben S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Pharmacotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Syed, Samina T.</au><au>Sharp, Lisa K.</au><au>Kim, Yoonsang</au><au>Jentleson, Adam</au><au>Lora, Claudia M.</au><au>Touchette, Daniel R.</au><au>Berbaum, Michael L.</au><au>Suda, Katie J.</au><au>Gerber, Ben S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus</atitle><jtitle>Pharmacotherapy</jtitle><addtitle>Pharmacotherapy</addtitle><date>2016-06</date><risdate>2016</risdate><volume>36</volume><issue>6</issue><spage>590</spage><epage>597</epage><pages>590-597</pages><issn>0277-0008</issn><eissn>1875-9114</eissn><abstract>Study Objective
To determine whether a relationship exists between medication adherence to angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) and distance to dispensing pharmacies and prescribers among an urban public aid population with diabetes mellitus.
Design
Retrospective cohort study using claims data.
Data Source
Illinois Department of Healthcare and Family Services database.
Patients
A total of 6532 patients aged 18–64 years with diabetes who had at least one prescription fill for an ACEI or ARB and had continuous Medicaid coverage in the greater Chicago area in 2009.
Measurements and Main Results
We assessed medication adherence, defined as proportion of days covered (PDC) of 0.8 or higher, to ACEIs and ARBs and its association with distances between patients and their pharmacies and prescribers. Of the 6532 patients included in the analyses, 2930 (45%) had PDC levels of 0.8 or higher. No significant differences were observed between patients who were adherent versus those who were nonadherent in distance to pharmacy (median 1.39 vs 1.35 miles, p=0.15) or distance to prescriber (median 4.39 vs 4.48 miles, p=0.80). In a multivariate regression model including age, sex, race/ethnicity, number of pharmacies, number of prescribers, distance to pharmacy, and distance to prescriber, a greater number of prescribers was associated with higher adherence (two prescribers vs one prescriber: odds ratio [OR] 1.396, 95% confidence interval [CI] 1.233–1.580; three or more prescribers vs one prescriber: OR 2.208, 95% CI 1.787–2.727).
Conclusion
ACEI or ARB adherence was not associated with distances to pharmacies and prescribers.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>27087250</pmid><doi>10.1002/phar.1757</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0277-0008 |
| ispartof | Pharmacotherapy, 2016-06, Vol.36 (6), p.590-597 |
| issn | 0277-0008 1875-9114 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4919160 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult angiotensin II receptor blocker Angiotensin Receptor Antagonists - therapeutic use angiotensin-converting enzyme inhibitor Angiotensin-Converting Enzyme Inhibitors - therapeutic use Confidence intervals Databases, Factual Diabetes diabetes mellitus Diabetes Mellitus - drug therapy Drug stores Female Geography, Medical - statistics & numerical data health services accessibility Humans Male medication adherence Medication Adherence - statistics & numerical data Middle Aged Pharmacies - statistics & numerical data Pharmacy Physicians - statistics & numerical data Retrospective Studies transportation Urban Population - statistics & numerical data Young Adult |
| title | Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus |
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