Prolonged dual antiplatelet therapy in stable coronary disease: comparative observational study of benefits and harms in unselected versus trial populations

Objective To estimate the potential magnitude in unselected patients of the benefits and harms of prolonged dual antiplatelet therapy after acute myocardial infarction seen in selected patients with high risk characteristics in trials.Design Observational population based cohort study.Setting PEGASU...

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Veröffentlicht in:	BMJ (Online) 2016-06, Vol.353, p.i3163
Hauptverfasser:	Timmis, A, Rapsomaniki, E, Chung, S C, Pujades-Rodriguez, M, Moayyeri, A, Stogiannis, D, Shah, A D, Pasea, L, Denaxas, S, Emmas, C, Hemingway, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Adenosine - administration & dosage Adenosine - adverse effects Adenosine - analogs & derivatives Aged Aged, 80 and over Angioplasty Anticoagulants Antiplatelet therapy Aspirin Aspirin - administration & dosage Aspirin - adverse effects Bleeding Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - mortality Cardiovascular Diseases - prevention & control Cause of Death Cerebral infarction Clinical trials Clinical Trials as Topic Codes Cohort Studies Coronary Disease - drug therapy Diabetes Drug Therapy, Combination Electronic Health Records Electronic medical records Female Heart attacks Heart diseases Hemorrhage - chemically induced Hospitals Humans Ischemia Kidney diseases Male Middle Aged Mortality Myocardial infarction Myocardial Infarction - prevention & control Patient admissions Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - adverse effects Population studies Primary care Risk assessment Risk Factors Secondary Prevention Stroke Stroke - prevention & control Ticagrelor Time Factors
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