Phylogeny-aware identification and correction of taxonomically mislabeled sequences

Molecular sequences in public databases are mostly annotated by the submitting authors without further validation. This procedure can generate erroneous taxonomic sequence labels. Mislabeled sequences are hard to identify, and they can induce downstream errors because new sequences are typically ann...

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Veröffentlicht in:	Nucleic acids research 2016-06, Vol.44 (11), p.5022-5033
Hauptverfasser:	Kozlov, Alexey M, Zhang, Jiajie, Yilmaz, Pelin, Glöckner, Frank Oliver, Stamatakis, Alexandros
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - genetics Computational Biology Computational Biology - methods Cyanobacteria Databases, Nucleic Acid DNA Barcoding, Taxonomic - standards Genomics - methods Molecular Sequence Annotation - standards Phylogeny Reproducibility of Results RNA, Ribosomal, 16S Sequence Analysis, DNA Software Web Browser
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