Dual Targeted Immunotherapy via In Vivo Delivery of Biohybrid RNAi-Peptide Nanoparticles to Tumor-Associated Macrophages and Cancer Cells

Lung cancer is associated with very poor prognosis and considered one of the leading causes of death worldwide. Here, highly potent and selective biohybrid RNA interference (RNAi)‐peptide nanoparticles (NPs) are presented that can induce specific and long‐lasting gene therapy in inflammatory tumor a...

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Veröffentlicht in:	Advanced functional materials 2015-07, Vol.25 (27), p.4183-4194
Hauptverfasser:	Conde, João, Bao, Chenchen, Tan, Yeqi, Cui, Daxiang, Edelman, Elazer R., Azevedo, Helena S., Byrne, Hugh J., Artzi, Natalie, Tian, Furong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Gene expression lung cancer Lungs Macrophages Mice Nanoparticles RNAi Survival tumor targeting tumor-associated macrophages Tumors
Online-Zugang:	Volltext
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