Apelin/APJ system： a novel promising therapy target for thrombotic diseases

APJ, which was initially identified as a gene with closest homology to the angiotensin II type 1 receptor, is a seven transmembrane G protein-coupled receptor. Apelin is an endogenous ligand of the APJ originally isolated from bovine stomach extracts.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Acta biochimica et biophysica Sinica 2016-06, Vol.48 (6), p.589-591
Hauptverfasser:	Li, Lanfang, Xu, Jin, Chen, Linxi, Jiang, Zhisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipokines - antagonists & inhibitors Adipokines - blood Adipokines - genetics Animals Apelin Apelin Receptors G蛋白偶联受体 Humans Intercellular Signaling Peptides and Proteins - blood Intercellular Signaling Peptides and Proteins - genetics Mice Platelet Activation - drug effects Platelet Activation - genetics Platelet Aggregation Inhibitors - therapeutic use Receptors, G-Protein-Coupled - antagonists & inhibitors Receptors, G-Protein-Coupled - blood Receptors, G-Protein-Coupled - genetics Research Highlight Thrombosis - blood Thrombosis - drug therapy Thrombosis - genetics 受体基因提取分离治疗系统血栓性疾病血管紧张素II
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	APJ, which was initially identified as a gene with closest homology to the angiotensin II type 1 receptor, is a seven transmembrane G protein-coupled receptor. Apelin is an endogenous ligand of the APJ originally isolated from bovine stomach extracts.
ISSN:	1672-9145 1745-7270
DOI:	10.1093/abbs/gmw028