Multicompartment metabolism in papillary thyroid cancer

Objectives/Hypothesis In many cancers, varying regions within the tumor are often phenotypically heterogeneous, including their metabolic phenotype. Further, tumor regions can be metabolically compartmentalized, with metabolites transferred between compartments. When present, this metabolic coupling...

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Veröffentlicht in:	The Laryngoscope 2016-10, Vol.126 (10), p.2410-2418
Hauptverfasser:	Curry, Joseph M., Tassone, Patrick, Cotzia, Paolo, Sprandio, John, Luginbuhl, Adam, Cognetti, David M., Mollaee, Mehri, Domingo-Vidal, Marina, Pribitkin, Edmund A., Keane, William M., Zhan, Tingting, Birbe, Ruth, Tuluc, Madalina, Martinez-Outschoorn, Ubaldo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - metabolism Adult Aged Biomarkers, Tumor - metabolism cancer Cancer-Associated Fibroblasts - physiology Carcinoma - metabolism Carcinoma, Papillary Case-Control Studies Cell Compartmentation - physiology coupling Female Fibroblasts Goiter, Nodular - metabolism Humans Immunohistochemistry Male Membrane Transport Proteins - analysis Metabolism Metabolites Middle Aged Monocarboxylic Acid Transporters - analysis Muscle Proteins - analysis papillary Receptors, Cell Surface - analysis thyroid Thyroid cancer Thyroid Cancer, Papillary Thyroid Neoplasms - metabolism Young Adult
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