Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking

Although alcoholism and depression are highly comorbid, treatment options that take this into account are lacking, and mouse models of alcohol (ethanol (EtOH)) intake-induced depressive-like behavior have not been well established. Recent studies utilizing contingent EtOH administration through prol...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2016-07, Vol.41 (8), p.2062-2071
Hauptverfasser:	Holleran, Katherine M, Wilson, Hadley H, Fetterly, Tracy L, Bluett, Rebecca J, Centanni, Samuel W, Gilfarb, Rachel A, Rocco, Lauren E R, Patel, Sachin, Winder, Danny G
Format:	Artikel
Sprache:	eng
Schlagworte:	Abstinence Addictive behaviors Affect - drug effects Alcohol Drinking Alcohol use Animals Antidepressants Anxiety Behavior Behavior, Animal - drug effects Benzodioxoles - administration & dosage Biophysics Comorbidity Depression - chemically induced Depression - prevention & control Drug abuse Endocannabinoids - metabolism Ethanol Ethanol - administration & dosage Excitatory Amino Acid Antagonists - administration & dosage Female Females Ketamine Ketamine - administration & dosage Mental depression Mice, Inbred C57BL Monoacylglycerol Lipases - antagonists & inhibitors Original Physiology Piperidines - administration & dosage Sucrose
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