SplAdder: identification, quantification and testing of alternative splicing events from RNA-Seq data

Understanding the occurrence and regulation of alternative splicing (AS) is a key task towards explaining the regulatory processes that shape the complex transcriptomes of higher eukaryotes. With the advent of high-throughput sequencing of RNA (RNA-Seq), the diversity of AS transcripts could be meas...

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Veröffentlicht in:Bioinformatics 2016-06, Vol.32 (12), p.1840-1847
Hauptverfasser: Kahles, André, Ong, Cheng Soon, Zhong, Yi, Rätsch, Gunnar
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Sprache:eng
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