Damage of vascular endothelial barrier induced by explosive blast and its clinical significance
In recent years, injuries induced by explosive blast have got more and more attention owing to weapon development and frequent terrorist activities. Tear, bleeding and edema of tissues and organs are the main manifestations of blast shock wave damage. Vascular endothelial barrier is the main defense...
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| Veröffentlicht in: | Chinese journal of traumatology 2016-06, Vol.19 (3), p.125-128 |
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| container_title | Chinese journal of traumatology |
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| creator | Wang, Jian-Min Chen, Jing |
| description | In recent years, injuries induced by explosive blast have got more and more attention owing to weapon development and frequent terrorist activities. Tear, bleeding and edema of tissues and organs are the main manifestations of blast shock wave damage. Vascular endothelial barrier is the main defense of tissues and organs＇ integrity. This article aims to discuss possible mechanisms of endothelial barrier damage induced by explosive blast and main manifestations of blood brain barrier, blood-air barrier, and intestinal vascular barrier impairments. In addition, the main regulatory factors of vascular permeability are also summarized so as to provide theoretical basis for prevention and cure of vascular endothelial barrier damaue resultinu from exolosive blast. |
| doi_str_mv | 10.1016/j.cjtee.2016.03.001 |
| format | Article |
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Tear, bleeding and edema of tissues and organs are the main manifestations of blast shock wave damage. Vascular endothelial barrier is the main defense of tissues and organs＇ integrity. This article aims to discuss possible mechanisms of endothelial barrier damage induced by explosive blast and main manifestations of blood brain barrier, blood-air barrier, and intestinal vascular barrier impairments. In addition, the main regulatory factors of vascular permeability are also summarized so as to provide theoretical basis for prevention and cure of vascular endothelial barrier damaue resultinu from exolosive blast.</description><identifier>ISSN: 1008-1275</identifier><identifier>DOI: 10.1016/j.cjtee.2016.03.001</identifier><identifier>PMID: 27321288</identifier><language>eng</language><publisher>China: Elsevier B.V</publisher><subject>Blast injuries ; Blast Injuries - metabolism ; Blood brain barrier ; Blood–air barrier ; Capillary Permeability ; Endothelium, Vascular - metabolism ; Humans ; Nitric Oxide - physiology ; Platelet Activating Factor - physiology ; Review ; Serotonin - physiology ; Thrombin - physiology ; Vascular endothelial cells ; 临床意义 ; 可能机制 ; 恐怖活动 ; 损伤 ; 爆炸冲击波 ; 爆炸性 ; 血管内皮 ; 血脑屏障</subject><ispartof>Chinese journal of traumatology, 2016-06, Vol.19 (3), p.125-128</ispartof><rights>2016</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>2016 Production and hosting by Elsevier B.V. on behalf of Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c520t-84204af52d4ec07f86cfdeadc66478fe91d059e883d8611d66e57ebd824846043</citedby><cites>FETCH-LOGICAL-c520t-84204af52d4ec07f86cfdeadc66478fe91d059e883d8611d66e57ebd824846043</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85114X/85114X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908223/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S100812751630061X$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,3537,27901,27902,53766,53768,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27321288$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Jian-Min</creatorcontrib><creatorcontrib>Chen, Jing</creatorcontrib><title>Damage of vascular endothelial barrier induced by explosive blast and its clinical significance</title><title>Chinese journal of traumatology</title><addtitle>Chinese Journal of Traumatology（English Edition）</addtitle><description>In recent years, injuries induced by explosive blast have got more and more attention owing to weapon development and frequent terrorist activities. Tear, bleeding and edema of tissues and organs are the main manifestations of blast shock wave damage. Vascular endothelial barrier is the main defense of tissues and organs＇ integrity. This article aims to discuss possible mechanisms of endothelial barrier damage induced by explosive blast and main manifestations of blood brain barrier, blood-air barrier, and intestinal vascular barrier impairments. In addition, the main regulatory factors of vascular permeability are also summarized so as to provide theoretical basis for prevention and cure of vascular endothelial barrier damaue resultinu from exolosive blast.</description><subject>Blast injuries</subject><subject>Blast Injuries - metabolism</subject><subject>Blood brain barrier</subject><subject>Blood–air barrier</subject><subject>Capillary Permeability</subject><subject>Endothelium, Vascular - metabolism</subject><subject>Humans</subject><subject>Nitric Oxide - physiology</subject><subject>Platelet Activating Factor - physiology</subject><subject>Review</subject><subject>Serotonin - physiology</subject><subject>Thrombin - physiology</subject><subject>Vascular endothelial cells</subject><subject>临床意义</subject><subject>可能机制</subject><subject>恐怖活动</subject><subject>损伤</subject><subject>爆炸冲击波</subject><subject>爆炸性</subject><subject>血管内皮</subject><subject>血脑屏障</subject><issn>1008-1275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUU1v1DAUzAFES-EXICGLExw2-CuO9wBSVcqHVIkLnC3Hfsk68tpbO1no_vp6ybaCEyfb8ryZeTNV9YrgmmAi3o-1GSeAmpZHjVmNMXlSnROM5YrQtjmrnuc8Yswpbtpn1RltGSVUyvNKfdJbPQCKPdrrbGavE4Jg47QB77RHnU7JQUIu2NmARd0dgt87H7PbA-q8zhPSwSI3ZWS8C86UmeyG4PpyDQZeVE977TO8PJ0X1c_P1z-uvq5uvn_5dnV5szINxdNKFmdc9w21HAxueylMb0FbIwRvZQ9rYnGzBimZlYIQKwQ0LXRWUi65wJxdVB8X3t3cbcEaCFPSXu2S2-p0p6J26t-f4DZqiHvF11hSygrBu4Xglw69DoMa45xCsawOG5MPBwXHbDEryRbs25NYircz5EltXTbgvQ4Q56xIu5YtZQstW6AmxZwT9I-WCFbH6tSo_lSnjvQKM7UIvP57m8eZh94K4MMCgJLpvhSksnFQ8rYugZmUje4_Am9OtjYxDLeu7PugIcSacC6IZPe5urpy</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Wang, Jian-Min</creator><creator>Chen, Jing</creator><general>Elsevier B.V</general><general>State Key Laboratory of Trauma,Burn and Combined Injury,Research Institute of Surgery/Daping Hospital,Third Military Medical University,Chongqing 400042,China</general><general>Elsevier</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope><scope>5PM</scope></search><sort><creationdate>20160601</creationdate><title>Damage of vascular endothelial barrier induced by explosive blast and its clinical significance</title><author>Wang, Jian-Min ; Chen, Jing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c520t-84204af52d4ec07f86cfdeadc66478fe91d059e883d8611d66e57ebd824846043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Blast injuries</topic><topic>Blast Injuries - metabolism</topic><topic>Blood brain barrier</topic><topic>Blood–air barrier</topic><topic>Capillary Permeability</topic><topic>Endothelium, Vascular - metabolism</topic><topic>Humans</topic><topic>Nitric Oxide - physiology</topic><topic>Platelet Activating Factor - physiology</topic><topic>Review</topic><topic>Serotonin - physiology</topic><topic>Thrombin - physiology</topic><topic>Vascular endothelial cells</topic><topic>临床意义</topic><topic>可能机制</topic><topic>恐怖活动</topic><topic>损伤</topic><topic>爆炸冲击波</topic><topic>爆炸性</topic><topic>血管内皮</topic><topic>血脑屏障</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Jian-Min</creatorcontrib><creatorcontrib>Chen, Jing</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chinese journal of traumatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Jian-Min</au><au>Chen, Jing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Damage of vascular endothelial barrier induced by explosive blast and its clinical significance</atitle><jtitle>Chinese journal of traumatology</jtitle><addtitle>Chinese Journal of Traumatology（English Edition）</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>19</volume><issue>3</issue><spage>125</spage><epage>128</epage><pages>125-128</pages><issn>1008-1275</issn><abstract>In recent years, injuries induced by explosive blast have got more and more attention owing to weapon development and frequent terrorist activities. Tear, bleeding and edema of tissues and organs are the main manifestations of blast shock wave damage. Vascular endothelial barrier is the main defense of tissues and organs＇ integrity. This article aims to discuss possible mechanisms of endothelial barrier damage induced by explosive blast and main manifestations of blood brain barrier, blood-air barrier, and intestinal vascular barrier impairments. In addition, the main regulatory factors of vascular permeability are also summarized so as to provide theoretical basis for prevention and cure of vascular endothelial barrier damaue resultinu from exolosive blast.</abstract><cop>China</cop><pub>Elsevier B.V</pub><pmid>27321288</pmid><doi>10.1016/j.cjtee.2016.03.001</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Chinese journal of traumatology, 2016-06, Vol.19 (3), p.125-128 |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Blast injuries Blast Injuries - metabolism Blood brain barrier Blood–air barrier Capillary Permeability Endothelium, Vascular - metabolism Humans Nitric Oxide - physiology Platelet Activating Factor - physiology Review Serotonin - physiology Thrombin - physiology Vascular endothelial cells 临床意义 可能机制 恐怖活动 损伤 爆炸冲击波 爆炸性 血管内皮 血脑屏障 |
| title | Damage of vascular endothelial barrier induced by explosive blast and its clinical significance |
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