Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape

The cistrome is the complete set of transcription factor (TF) binding sites (cis-elements) in an organism, while an epicistrome incorporates tissue-specific DNA chemical modifications and TF-specific chemical sensitivities into these binding profiles. Robust methods to construct comprehensive cistro...

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Veröffentlicht in:	Cell 2016-05, Vol.165 (5), p.1280-1292
Hauptverfasser:	O’Malley, Ronan C., Huang, Shao-shan Carol, Song, Liang, Lewsey, Mathew G., Bartlett, Anna, Nery, Joseph R., Galli, Mary, Gallavotti, Andrea, Ecker, Joseph R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Arabidopsis Arabidopsis - genetics binding sites cost effectiveness data collection DNA DNA, Plant - genetics DNA, Plant - metabolism Epigenesis, Genetic gene regulatory networks Genome, Plant Indoleacetic Acids - metabolism landscapes methylation Plant Proteins - genetics Response Elements Sequence Analysis, DNA - methods transcription factors Transcription Factors - metabolism
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