Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice

Inhibition of the mTOR (mechanistic target of rapamycin) signaling pathway by the FDA-approved drug rapamycin promotes life span in numerous model organisms and delays age-related disease in mice. However, the utilization of rapamycin as a therapy for age-related diseases will likely prove challengi...

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Veröffentlicht in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2016-07, Vol.71 (7), p.876-881
Hauptverfasser: Arriola Apelo, Sebastian I, Pumper, Cassidy P, Baar, Emma L, Cummings, Nicole E, Lamming, Dudley W
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Sprache:eng
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