Cerebral White Matter and Slow Gait: Contribution of Hyperintensities and Normal-appearing Parenchyma

White matter hyperintensities (WMH), a common marker of cerebral small vessel disease, and lower microstructural integrity of normal-appearing white matter are associated with slower gait. How these cerebral measures interact in relation to slower gait is unknown. We assessed whether microstructural...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2016-07, Vol.71 (7), p.968-973
Hauptverfasser:	Rosario, Bedda L, Rosso, Andrea L, Aizenstein, Howard J, Harris, Tamara, Newman, Anne B, Satterfield, Suzanne, Studenski, Stephanie A, Yaffe, Kristine, Rosano, Caterina
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging - physiology Anisotropy Biomarkers Brain Corpus Callosum - diagnostic imaging Corpus Callosum - pathology Diffusion Tensor Imaging - methods Female Gait - physiology Gerontology Gyrus Cinguli - diagnostic imaging Gyrus Cinguli - pathology Humans Leukoencephalopathies - complications Leukoencephalopathies - pathology Leukoencephalopathies - physiopathology Male Medical disorders Mobility NMR Nuclear magnetic resonance Risk Factors Statistics as Topic Walking Speed - physiology White Matter - diagnostic imaging White Matter - pathology
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