Patch-Clamp Study of Hepatitis C p7 Channels Reveals Genotype-Specific Sensitivity to Inhibitors

Hepatitis C is a major worldwide disease and health hazard, affecting ∼3% of the world population. The p7 protein of hepatitis C virus (HCV) is an intracellular ion channel and pH regulator that is involved in the viral replication cycle. It is targeted by various classical ion channel blockers. Her...

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Veröffentlicht in:Biophysical journal 2016-06, Vol.110 (11), p.2419-2429
Hauptverfasser: Breitinger, Ulrike, Farag, Noha S., Ali, Nourhan K.M., Breitinger, Hans-Georg A.
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Sprache:eng
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