The LIM domain protein nTRIP6 acts as a co-repressor for the transcription factor MEF2C in myoblasts

The transcription factor Myocyte enhancer factor 2C (MEF2C) plays a key role in the late differentiation of skeletal muscle progenitor cells, the so-called myoblasts. During myoblast differentiation, both MEF2C expression and transcriptional activity are regulated. We have reported that nTRIP6, the...

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Veröffentlicht in:	Scientific reports 2016-06, Vol.6 (1), p.27746, Article 27746
Hauptverfasser:	Kemler, Denise, Dahley, Oliver, Roßwag, Sven, Litfin, Margarethe, Kassel, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	14/19 14/35 38 38/109 38/15 38/77 631/136/142 631/208/200 631/337/572 Adaptor Proteins, Signal Transducing - chemistry Adaptor Proteins, Signal Transducing - metabolism Adhesion Animals Antibodies Binding Sites Cell Differentiation Cell Line Cell Nucleus - metabolism Cell Proliferation Connectin - genetics Humanities and Social Sciences LIM Domain Proteins - chemistry LIM Domain Proteins - metabolism Localization MEF2 Transcription Factors - metabolism Mice multidisciplinary Myoblasts - cytology Myoblasts - metabolism Myogenesis Promoter Regions, Genetic Protein Binding Protein Domains Proteins Regulation Science Transcription factors Transcription Factors - chemistry Transcription Factors - metabolism Troponin I - genetics Yeasts
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