Total body irradiation-an attachment free sweeping beam technique
A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung shielding is facilitated to reduce the risk of pulmonary toxicity. Additionally, the applicab...
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Veröffentlicht in: | Radiation oncology (London, England) England), 2016-06, Vol.11 (1), p.81, Article 81 |
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creator | Härtl, Petra M Treutwein, Marius Hautmann, Matthias G März, Manuel Pohl, Fabian Kölbl, Oliver Dobler, Barbara |
description | A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung shielding is facilitated to reduce the risk of pulmonary toxicity. Additionally, the applicability of a commercial radiotherapy planning system (RTPS) is examined.
The patient is positioned on a low couch on the floor, the longitudinal axis of the body in the rotational plane of the linac. Eight arc fields and five additional fixed beams are applied to the patient in supine and prone position respectively. The dose distributions were measured in a solid water phantom and in an Alderson phantom. Diode detectors were calibrated for in-vivo dosimetry. The RTPS Oncentra was employed for calculations of the dose distribution.
For the cranial 120 cm the longitudinal dose profile in a slab phantom measured with ionization chamber varies between 94 and 107 % of the prescription dose. These values were confirmed by film measurements and RTPS calculations. The transmittance of the lung shields has been determined as a function of the thickness of the absorber material. Measurements in an Alderson phantom and in-vivo dosimetry of the first patients match the calculated dose.
A treatment technique with clinically good dose distributions has been introduced, which can be applied with each standard linac and in standard treatment rooms. Dose calculations were performed with a commercial RTPS and should enable individual dose optimization. |
doi_str_mv | 10.1186/s13014-016-0658-y |
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The patient is positioned on a low couch on the floor, the longitudinal axis of the body in the rotational plane of the linac. Eight arc fields and five additional fixed beams are applied to the patient in supine and prone position respectively. The dose distributions were measured in a solid water phantom and in an Alderson phantom. Diode detectors were calibrated for in-vivo dosimetry. The RTPS Oncentra was employed for calculations of the dose distribution.
For the cranial 120 cm the longitudinal dose profile in a slab phantom measured with ionization chamber varies between 94 and 107 % of the prescription dose. These values were confirmed by film measurements and RTPS calculations. The transmittance of the lung shields has been determined as a function of the thickness of the absorber material. Measurements in an Alderson phantom and in-vivo dosimetry of the first patients match the calculated dose.
A treatment technique with clinically good dose distributions has been introduced, which can be applied with each standard linac and in standard treatment rooms. Dose calculations were performed with a commercial RTPS and should enable individual dose optimization.</description><identifier>ISSN: 1748-717X</identifier><identifier>EISSN: 1748-717X</identifier><identifier>DOI: 10.1186/s13014-016-0658-y</identifier><identifier>PMID: 27287010</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Calibration ; Hematopoietic stem cells ; Humans ; Lung - radiation effects ; Methods ; Organ Sparing Treatments ; Particle Accelerators ; Patient Care Planning ; Phantoms, Imaging ; Radiation Injuries - prevention & control ; Radiometry - instrumentation ; Radiotherapy ; Radiotherapy Planning, Computer-Assisted - methods ; Transplantation ; Whole-Body Irradiation - methods</subject><ispartof>Radiation oncology (London, England), 2016-06, Vol.11 (1), p.81, Article 81</ispartof><rights>COPYRIGHT 2016 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2016</rights><rights>The Author(s). 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-92512c240562031d1234167726b1210a2bd98de4964b7ade1a8a70faf0b87e8b3</citedby><cites>FETCH-LOGICAL-c494t-92512c240562031d1234167726b1210a2bd98de4964b7ade1a8a70faf0b87e8b3</cites><orcidid>0000-0002-6538-9980</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902948/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902948/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27287010$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Härtl, Petra M</creatorcontrib><creatorcontrib>Treutwein, Marius</creatorcontrib><creatorcontrib>Hautmann, Matthias G</creatorcontrib><creatorcontrib>März, Manuel</creatorcontrib><creatorcontrib>Pohl, Fabian</creatorcontrib><creatorcontrib>Kölbl, Oliver</creatorcontrib><creatorcontrib>Dobler, Barbara</creatorcontrib><title>Total body irradiation-an attachment free sweeping beam technique</title><title>Radiation oncology (London, England)</title><addtitle>Radiat Oncol</addtitle><description>A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung shielding is facilitated to reduce the risk of pulmonary toxicity. Additionally, the applicability of a commercial radiotherapy planning system (RTPS) is examined.
The patient is positioned on a low couch on the floor, the longitudinal axis of the body in the rotational plane of the linac. Eight arc fields and five additional fixed beams are applied to the patient in supine and prone position respectively. The dose distributions were measured in a solid water phantom and in an Alderson phantom. Diode detectors were calibrated for in-vivo dosimetry. The RTPS Oncentra was employed for calculations of the dose distribution.
For the cranial 120 cm the longitudinal dose profile in a slab phantom measured with ionization chamber varies between 94 and 107 % of the prescription dose. These values were confirmed by film measurements and RTPS calculations. The transmittance of the lung shields has been determined as a function of the thickness of the absorber material. Measurements in an Alderson phantom and in-vivo dosimetry of the first patients match the calculated dose.
A treatment technique with clinically good dose distributions has been introduced, which can be applied with each standard linac and in standard treatment rooms. Dose calculations were performed with a commercial RTPS and should enable individual dose optimization.</description><subject>Calibration</subject><subject>Hematopoietic stem cells</subject><subject>Humans</subject><subject>Lung - radiation effects</subject><subject>Methods</subject><subject>Organ Sparing Treatments</subject><subject>Particle Accelerators</subject><subject>Patient Care Planning</subject><subject>Phantoms, Imaging</subject><subject>Radiation Injuries - prevention & control</subject><subject>Radiometry - instrumentation</subject><subject>Radiotherapy</subject><subject>Radiotherapy Planning, Computer-Assisted - methods</subject><subject>Transplantation</subject><subject>Whole-Body Irradiation - methods</subject><issn>1748-717X</issn><issn>1748-717X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkU9r3DAQxUVJadK0HyCXYMjZ6YwsS_IlsIS2KQR6SaE3MZblXYW1tJG8Cfvtq7D5C0WHEZr3Hk_8GDtBOEfU8lvGBlDUgLIG2ep694EdoRK6Vqj-Hry5H7LPOd8CiLaB7hM75IprBQhHbHETZ1pXfRx2lU-JBk-zj6GmUNE8k11NLszVmJyr8oNzGx-WVe9oqmZnV8Hfbd0X9nGkdXZfn-Yx-_Pj-83lVX39--evy8V1bUUn5rrjLXLLBbSSQ4MD8kagVIrLHjkC8X7o9OBEJ0WvaHBImhSMNEKvldN9c8wu9rmbbT-5wZZeidZmk_xEaWciefN-E_zKLOO9ER3wTugScPYUkGLpnWdzG7cplM4GNYCWWkn1qlrS2hkfxljC7OSzNQshtVZKtaKozv-jKmdwk7cxuNGX93cG3BtsijknN74URzCPMM0epikwzSNMsyue07c_fnE802v-Ab72mYk</recordid><startdate>20160610</startdate><enddate>20160610</enddate><creator>Härtl, Petra M</creator><creator>Treutwein, Marius</creator><creator>Hautmann, Matthias G</creator><creator>März, Manuel</creator><creator>Pohl, Fabian</creator><creator>Kölbl, Oliver</creator><creator>Dobler, Barbara</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6538-9980</orcidid></search><sort><creationdate>20160610</creationdate><title>Total body irradiation-an attachment free sweeping beam technique</title><author>Härtl, Petra M ; Treutwein, Marius ; Hautmann, Matthias G ; März, Manuel ; Pohl, Fabian ; Kölbl, Oliver ; Dobler, Barbara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-92512c240562031d1234167726b1210a2bd98de4964b7ade1a8a70faf0b87e8b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Calibration</topic><topic>Hematopoietic stem cells</topic><topic>Humans</topic><topic>Lung - radiation effects</topic><topic>Methods</topic><topic>Organ Sparing Treatments</topic><topic>Particle Accelerators</topic><topic>Patient Care Planning</topic><topic>Phantoms, Imaging</topic><topic>Radiation Injuries - prevention & control</topic><topic>Radiometry - instrumentation</topic><topic>Radiotherapy</topic><topic>Radiotherapy Planning, Computer-Assisted - methods</topic><topic>Transplantation</topic><topic>Whole-Body Irradiation - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Härtl, Petra M</creatorcontrib><creatorcontrib>Treutwein, Marius</creatorcontrib><creatorcontrib>Hautmann, Matthias G</creatorcontrib><creatorcontrib>März, Manuel</creatorcontrib><creatorcontrib>Pohl, Fabian</creatorcontrib><creatorcontrib>Kölbl, Oliver</creatorcontrib><creatorcontrib>Dobler, Barbara</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Radiation oncology (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Härtl, Petra M</au><au>Treutwein, Marius</au><au>Hautmann, Matthias G</au><au>März, Manuel</au><au>Pohl, Fabian</au><au>Kölbl, Oliver</au><au>Dobler, Barbara</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Total body irradiation-an attachment free sweeping beam technique</atitle><jtitle>Radiation oncology (London, England)</jtitle><addtitle>Radiat Oncol</addtitle><date>2016-06-10</date><risdate>2016</risdate><volume>11</volume><issue>1</issue><spage>81</spage><pages>81-</pages><artnum>81</artnum><issn>1748-717X</issn><eissn>1748-717X</eissn><abstract>A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung shielding is facilitated to reduce the risk of pulmonary toxicity. Additionally, the applicability of a commercial radiotherapy planning system (RTPS) is examined.
The patient is positioned on a low couch on the floor, the longitudinal axis of the body in the rotational plane of the linac. Eight arc fields and five additional fixed beams are applied to the patient in supine and prone position respectively. The dose distributions were measured in a solid water phantom and in an Alderson phantom. Diode detectors were calibrated for in-vivo dosimetry. The RTPS Oncentra was employed for calculations of the dose distribution.
For the cranial 120 cm the longitudinal dose profile in a slab phantom measured with ionization chamber varies between 94 and 107 % of the prescription dose. These values were confirmed by film measurements and RTPS calculations. The transmittance of the lung shields has been determined as a function of the thickness of the absorber material. Measurements in an Alderson phantom and in-vivo dosimetry of the first patients match the calculated dose.
A treatment technique with clinically good dose distributions has been introduced, which can be applied with each standard linac and in standard treatment rooms. Dose calculations were performed with a commercial RTPS and should enable individual dose optimization.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>27287010</pmid><doi>10.1186/s13014-016-0658-y</doi><orcidid>https://orcid.org/0000-0002-6538-9980</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Calibration Hematopoietic stem cells Humans Lung - radiation effects Methods Organ Sparing Treatments Particle Accelerators Patient Care Planning Phantoms, Imaging Radiation Injuries - prevention & control Radiometry - instrumentation Radiotherapy Radiotherapy Planning, Computer-Assisted - methods Transplantation Whole-Body Irradiation - methods |
title | Total body irradiation-an attachment free sweeping beam technique |
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