Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation

Genome-wide association studies (GWAS) have identified multiple genetic loci for C-reactive protein (CRP) and lipids, of which some overlap. We aimed to identify genetic pleiotropy among CRP and lipids in order to better understand the shared biology of chronic inflammation and lipid metabolism. In...

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Veröffentlicht in:	BMC genomics 2016-06, Vol.17 (1), p.443-443, Article 443
Hauptverfasser:	Ligthart, Symen, Vaez, Ahmad, Hsu, Yi-Hsiang, Stolk, Ronald, Uitterlinden, André G, Hofman, Albert, Alizadeh, Behrooz Z, Franco, Oscar H, Dehghan, Abbas
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biomarkers C-Reactive Protein Cholesterol, HDL DNA Replication Gene Expression Genetic Association Studies Genome-wide association studies Genome-Wide Association Study Genomics Inflammation Inflammation - genetics Lipid metabolism Lipid Metabolism - genetics Multifactorial Inheritance Polymorphism, Single Nucleotide Quantitative Trait Loci Triglycerides
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