Epidermal growth factor receptor targeting and challenges in glioblastoma

With the evolution of technology, there is now a deeper understanding of glioblastoma as an inter- and intraheterogeneous disease comprising a multitude of genetically and epigenetically different cancer cells. Greater characterization of glioblastoma at the molecular level has improved its initial...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2016-07, Vol.18 (7), p.914-918
Hauptverfasser:	Thorne, Amy Haseley, Zanca, Ciro, Furnari, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Neoplasms - drug therapy Brain Neoplasms - metabolism Drug Resistance, Neoplasm - drug effects Glioblastoma - drug therapy Glioblastoma - metabolism Humans Invited Reviews Receptor, Epidermal Growth Factor - metabolism Signal Transduction - drug effects
Online-Zugang:	Volltext
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