Measurement of IL‐12 (p40, p35), IL‐23p19, and IFN‐γ mRNA in Duodenal Biopsies of Cats with Inflammatory Enteropathy

BACKGROUND: Dietary hypersensitivity and inflammatory bowel disease (IBD) are important causes of chronic vomiting and diarrhea in cats. IL‐23 has been recently found to be a key factor in the immunopathogenesis of IBD in humans but the involvement in IBD has not been investigated in cats. HYPOTHESI...

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Veröffentlicht in:	Journal of veterinary internal medicine 2014-01, Vol.28 (1), p.42-47
Hauptverfasser:	Waly, N.E, Peters, I.R, Day, M.J, Stokes, C.R, Bailey, M, Gruffydd‐Jones, T.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biopsy Biopsy - veterinary Cat Diseases - genetics Cat Diseases - immunology Cat Diseases - pathology Cats colitis Crohn's disease Cytokines diarrhea Dietary hypersensitivity Food-responsive diarrhea GALT gene expression gene expression regulation Gene Expression Regulation - immunology genes histopathology humans hypersensitivity immunohistochemistry Immunohistochemistry - veterinary inflammation Inflammatory bowel disease Inflammatory Bowel Diseases - genetics Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - pathology Inflammatory Bowel Diseases - veterinary interferon-gamma Interferon-gamma - genetics Interferon-gamma - immunology interleukin-12 Interleukin-12 Subunit p35 - genetics Interleukin-12 Subunit p35 - immunology Interleukin-12 Subunit p40 - genetics Interleukin-12 Subunit p40 - immunology interleukin-23 Interleukin-23 Subunit p19 - genetics Interleukin-23 Subunit p19 - immunology medicine messenger RNA mucosa Original Pathogenesis reverse transcriptase polymerase chain reaction Reverse Transcriptase Polymerase Chain Reaction - veterinary RNA - chemistry RNA - genetics Statistics, Nonparametric vomiting
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