Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury

Acute kidney injury (AKI) is an abrupt reduction in kidney function caused by different pathological processes. It is associated with a significant morbidity and mortality in the acute phase and an increased risk of developing End Stage Renal Disease. Despite the progress in the management of the di...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2016-06, Vol.6 (1), p.27112, Article 27112
Hauptverfasser:	Cocchiaro, Pasquale, Fox, Christopher, Tregidgo, Nicholas W., Howarth, Rachel, Wood, Katrina M., Situmorang, Gerhard R., Pavone, Luigi M., Sheerin, Neil S., Moles, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 13/51 14/19 14/63 38 38/77 38/79 631/80/82 692/4022/1585/4 Acute Kidney Injury - drug therapy Acute Kidney Injury - etiology Acute Kidney Injury - metabolism Acute Kidney Injury - physiopathology Animals Apoptosis Cathepsin D - metabolism Cell death Cell Line Creatinine Disease Models, Animal Folic Acid - adverse effects Humanities and Social Sciences Humans Ischemia Kidney Function Tests Kidney transplantation Kidney Tubules - cytology Kidney Tubules - drug effects Kidney Tubules - enzymology Kidneys Kinases Male Mice Mortality multidisciplinary Nephrosis - chemically induced Nephrosis - complications Nephrosis - drug therapy Nephrosis - enzymology Pepstatins - administration & dosage Pepstatins - pharmacology Reperfusion Injury - complications Reperfusion Injury - drug therapy Science Science (multidisciplinary) Up-Regulation Vitamin B
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!