Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection. Case report. A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease,...
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Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2016-05, Vol.8 (5), p.e597 |
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creator | Chin-Loy, Katrina Galaydh, Farah Shaikh, Saad |
description | We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection.
Case report.
A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.
The authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug. |
doi_str_mv | 10.7759/cureus.597 |
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Case report.
A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.
The authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.597</identifier><identifier>PMID: 27335709</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Antiviral drugs ; Case reports ; Hepatitis C ; Ophthalmology</subject><ispartof>Curēus (Palo Alto, CA), 2016-05, Vol.8 (5), p.e597</ispartof><rights>Copyright © 2016, Chin-Loy et al. This work is licensed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2016, Chin-Loy et al. 2016 Chin-Loy et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895080/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895080/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27335709$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chin-Loy, Katrina</creatorcontrib><creatorcontrib>Galaydh, Farah</creatorcontrib><creatorcontrib>Shaikh, Saad</creatorcontrib><title>Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection.
Case report.
A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.
The authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug.</description><subject>Antiviral drugs</subject><subject>Case reports</subject><subject>Hepatitis C</subject><subject>Ophthalmology</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkU9LAzEQxYMoKrUXP4AEvAmt-bebzUWQorYgCGpvQkizEzeim5pkK_32rq2KnmZg3vzmMQ-hY0rGUhbq3HYRujQulNxBh4yW1aiildj90x-gYUovhBBKJCOS7KMDJjkvJFGH6Okesm_D0uRmjU1b4_kKfPYJX6YUrDcZavzhc4Mfggtp0a18xI8NRLNcYxcinjQxtN7iKfSIzeIEz1oHNvvQHqE9Z14TDL_rAM2vrx4n09Ht3c1scnk7sqxkecQsgVJYEIoaJgnhNbEl5dYIcLSmYgGEMQeqYsI6KpWxVvHaCcst0IIt-ABdbLnLbvEGtYU2R_Oql9G_mbjWwXj9f9L6Rj-HlRaVKkhFesDpNyCG9w5S1i-hi23vWVNVcMHLcqM626psDClFcL8XKNFfYehtGLoPoxef_PX0K_15Pf8EO5CIdA</recordid><startdate>20160503</startdate><enddate>20160503</enddate><creator>Chin-Loy, Katrina</creator><creator>Galaydh, Farah</creator><creator>Shaikh, Saad</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20160503</creationdate><title>Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection</title><author>Chin-Loy, Katrina ; Galaydh, Farah ; Shaikh, Saad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c262t-2c0e64ce491a27003d0c613ca4ef1d14be022fe9824cf179acc93df4c3ce152b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Antiviral drugs</topic><topic>Case reports</topic><topic>Hepatitis C</topic><topic>Ophthalmology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chin-Loy, Katrina</creatorcontrib><creatorcontrib>Galaydh, Farah</creatorcontrib><creatorcontrib>Shaikh, Saad</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chin-Loy, Katrina</au><au>Galaydh, Farah</au><au>Shaikh, Saad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2016-05-03</date><risdate>2016</risdate><volume>8</volume><issue>5</issue><spage>e597</spage><pages>e597-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection.
Case report.
A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.
The authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>27335709</pmid><doi>10.7759/cureus.597</doi><oa>free_for_read</oa></addata></record> |
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source | PubMed Central Open Access; PubMed Central |
subjects | Antiviral drugs Case reports Hepatitis C Ophthalmology |
title | Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection |
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