Frailty predicts trajectories of quality of life over time among British community-dwelling older people
Purpose To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL...
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| Veröffentlicht in: | Quality of life research 2016-07, Vol.25 (7), p.1743-1750 |
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| creator | Kojima, Gotaro Iliffe, Steve Morris, Richard W. Taniguchi, Yu Kendrick, Denise Skelton, Dawn A. Masud, Tahir Bowling, Ann |
| description | Purpose To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People's Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. Results At baseline, mean age was 73.1 (range 65-90) and 62.0 % were women. Mean FI was 0.17 (range 0.00-0.66), and mean OPQOL was 130.80 (range 93-163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = —47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to -1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. Conclusions Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined. |
| doi_str_mv | 10.1007/s11136-015-1213-2 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4893360</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>44852935</jstor_id><sourcerecordid>44852935</sourcerecordid><originalsourceid>FETCH-LOGICAL-c558t-1927e36054fa9008ea0cff4625392cd5b5e85e10e17dc1ad052815c95cd2162f3</originalsourceid><addsrcrecordid>eNp9kU9v1DAQxS0EokvhA3AAReLCJa3Hf5L4ggQVhUqVuJSz5TqTXa-SOLWTon57ZpWyKhw4zUjzmzfz9Bh7C_wMOK_PMwDIquSgSxAgS_GMbUDX1FTKPGcbbipRGqnkCXuV855z3hguXrITUdWqltBs2O4yudDPD8WUsA1-zsWc3B79HFPAXMSuuFtcHwigtg8dFvEeUzGHAQs3xHFbfElhDnlX-DgMy0hk2f7Cvg80in1L7IRx6vE1e9G5PuObx3rKfl5-vbn4Xl7_-HZ18fm69Fo3cwlG1CgrrlXnDP2LjvuuU5XQ0gjf6luNjUbgCHXrwbVciwa0N9q3AirRyVP2adWdltsBW48jGertlMLg0oONLti_J2PY2W28t6oxkg6TwMdHgRTvFsyzHUL25MiNGJdsoTZKVU2lDaEf_kH3cUkj2TtQsjam1kAUrJRPMeeE3fEZ4PaQo11ztJSjPeRoBe28f-riuPEnOALECmQajVtMT07_R_XdurTPlO9RVKlGCyO1_A1saLO7</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1793799751</pqid></control><display><type>article</type><title>Frailty predicts trajectories of quality of life over time among British community-dwelling older people</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>SpringerLink Journals - AutoHoldings</source><creator>Kojima, Gotaro ; Iliffe, Steve ; Morris, Richard W. ; Taniguchi, Yu ; Kendrick, Denise ; Skelton, Dawn A. ; Masud, Tahir ; Bowling, Ann</creator><creatorcontrib>Kojima, Gotaro ; Iliffe, Steve ; Morris, Richard W. ; Taniguchi, Yu ; Kendrick, Denise ; Skelton, Dawn A. ; Masud, Tahir ; Bowling, Ann</creatorcontrib><description>Purpose To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People's Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. Results At baseline, mean age was 73.1 (range 65-90) and 62.0 % were women. Mean FI was 0.17 (range 0.00-0.66), and mean OPQOL was 130.80 (range 93-163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = —47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to -1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. Conclusions Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.</description><identifier>ISSN: 0962-9343</identifier><identifier>EISSN: 1573-2649</identifier><identifier>DOI: 10.1007/s11136-015-1213-2</identifier><identifier>PMID: 26747318</identifier><language>eng</language><publisher>Cham: Springer</publisher><subject>Activities of daily living ; Aged ; Aged, 80 and over ; CLINICAL AND POLICY APPLICATIONS ; Clinical trials ; Comorbidity ; Ethnic Groups ; Ethnicity ; Exercise ; Female ; Frail Elderly - statistics & numerical data ; Frailty ; Genotype & phenotype ; Geriatric Assessment ; Geriatrics ; Gerontology ; Humans ; Male ; Medicine ; Medicine & Public Health ; Older adults ; Older people ; Phenotypes ; Physical fitness ; Primary care ; Public Health ; Quality of Life ; Quality of Life Research ; Questionnaires ; Residence Characteristics - statistics & numerical data ; Sociology ; Surveys and Questionnaires ; United Kingdom ; Wellbeing</subject><ispartof>Quality of life research, 2016-07, Vol.25 (7), p.1743-1750</ispartof><rights>Springer International Publishing 2016</rights><rights>The Author(s) 2016</rights><rights>Springer International Publishing Switzerland 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c558t-1927e36054fa9008ea0cff4625392cd5b5e85e10e17dc1ad052815c95cd2162f3</citedby><cites>FETCH-LOGICAL-c558t-1927e36054fa9008ea0cff4625392cd5b5e85e10e17dc1ad052815c95cd2162f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44852935$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44852935$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,780,784,803,885,27923,27924,41487,42556,51318,58016,58249</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26747318$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kojima, Gotaro</creatorcontrib><creatorcontrib>Iliffe, Steve</creatorcontrib><creatorcontrib>Morris, Richard W.</creatorcontrib><creatorcontrib>Taniguchi, Yu</creatorcontrib><creatorcontrib>Kendrick, Denise</creatorcontrib><creatorcontrib>Skelton, Dawn A.</creatorcontrib><creatorcontrib>Masud, Tahir</creatorcontrib><creatorcontrib>Bowling, Ann</creatorcontrib><title>Frailty predicts trajectories of quality of life over time among British community-dwelling older people</title><title>Quality of life research</title><addtitle>Qual Life Res</addtitle><addtitle>Qual Life Res</addtitle><description>Purpose To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People's Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. Results At baseline, mean age was 73.1 (range 65-90) and 62.0 % were women. Mean FI was 0.17 (range 0.00-0.66), and mean OPQOL was 130.80 (range 93-163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = —47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to -1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. Conclusions Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.</description><subject>Activities of daily living</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>CLINICAL AND POLICY APPLICATIONS</subject><subject>Clinical trials</subject><subject>Comorbidity</subject><subject>Ethnic Groups</subject><subject>Ethnicity</subject><subject>Exercise</subject><subject>Female</subject><subject>Frail Elderly - statistics & numerical data</subject><subject>Frailty</subject><subject>Genotype & phenotype</subject><subject>Geriatric Assessment</subject><subject>Geriatrics</subject><subject>Gerontology</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Older adults</subject><subject>Older people</subject><subject>Phenotypes</subject><subject>Physical fitness</subject><subject>Primary care</subject><subject>Public Health</subject><subject>Quality of Life</subject><subject>Quality of Life Research</subject><subject>Questionnaires</subject><subject>Residence Characteristics - statistics & numerical data</subject><subject>Sociology</subject><subject>Surveys and Questionnaires</subject><subject>United Kingdom</subject><subject>Wellbeing</subject><issn>0962-9343</issn><issn>1573-2649</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU9v1DAQxS0EokvhA3AAReLCJa3Hf5L4ggQVhUqVuJSz5TqTXa-SOLWTon57ZpWyKhw4zUjzmzfz9Bh7C_wMOK_PMwDIquSgSxAgS_GMbUDX1FTKPGcbbipRGqnkCXuV855z3hguXrITUdWqltBs2O4yudDPD8WUsA1-zsWc3B79HFPAXMSuuFtcHwigtg8dFvEeUzGHAQs3xHFbfElhDnlX-DgMy0hk2f7Cvg80in1L7IRx6vE1e9G5PuObx3rKfl5-vbn4Xl7_-HZ18fm69Fo3cwlG1CgrrlXnDP2LjvuuU5XQ0gjf6luNjUbgCHXrwbVciwa0N9q3AirRyVP2adWdltsBW48jGertlMLg0oONLti_J2PY2W28t6oxkg6TwMdHgRTvFsyzHUL25MiNGJdsoTZKVU2lDaEf_kH3cUkj2TtQsjam1kAUrJRPMeeE3fEZ4PaQo11ztJSjPeRoBe28f-riuPEnOALECmQajVtMT07_R_XdurTPlO9RVKlGCyO1_A1saLO7</recordid><startdate>20160701</startdate><enddate>20160701</enddate><creator>Kojima, Gotaro</creator><creator>Iliffe, Steve</creator><creator>Morris, Richard W.</creator><creator>Taniguchi, Yu</creator><creator>Kendrick, Denise</creator><creator>Skelton, Dawn A.</creator><creator>Masud, Tahir</creator><creator>Bowling, Ann</creator><general>Springer</general><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>KB0</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160701</creationdate><title>Frailty predicts trajectories of quality of life over time among British community-dwelling older people</title><author>Kojima, Gotaro ; Iliffe, Steve ; Morris, Richard W. ; Taniguchi, Yu ; Kendrick, Denise ; Skelton, Dawn A. ; Masud, Tahir ; Bowling, Ann</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c558t-1927e36054fa9008ea0cff4625392cd5b5e85e10e17dc1ad052815c95cd2162f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Activities of daily living</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>CLINICAL AND POLICY APPLICATIONS</topic><topic>Clinical trials</topic><topic>Comorbidity</topic><topic>Ethnic Groups</topic><topic>Ethnicity</topic><topic>Exercise</topic><topic>Female</topic><topic>Frail Elderly - statistics & numerical data</topic><topic>Frailty</topic><topic>Genotype & phenotype</topic><topic>Geriatric Assessment</topic><topic>Geriatrics</topic><topic>Gerontology</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Older adults</topic><topic>Older people</topic><topic>Phenotypes</topic><topic>Physical fitness</topic><topic>Primary care</topic><topic>Public Health</topic><topic>Quality of Life</topic><topic>Quality of Life Research</topic><topic>Questionnaires</topic><topic>Residence Characteristics - statistics & numerical data</topic><topic>Sociology</topic><topic>Surveys and Questionnaires</topic><topic>United Kingdom</topic><topic>Wellbeing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kojima, Gotaro</creatorcontrib><creatorcontrib>Iliffe, Steve</creatorcontrib><creatorcontrib>Morris, Richard W.</creatorcontrib><creatorcontrib>Taniguchi, Yu</creatorcontrib><creatorcontrib>Kendrick, Denise</creatorcontrib><creatorcontrib>Skelton, Dawn A.</creatorcontrib><creatorcontrib>Masud, Tahir</creatorcontrib><creatorcontrib>Bowling, Ann</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Global</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Quality of life research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kojima, Gotaro</au><au>Iliffe, Steve</au><au>Morris, Richard W.</au><au>Taniguchi, Yu</au><au>Kendrick, Denise</au><au>Skelton, Dawn A.</au><au>Masud, Tahir</au><au>Bowling, Ann</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frailty predicts trajectories of quality of life over time among British community-dwelling older people</atitle><jtitle>Quality of life research</jtitle><stitle>Qual Life Res</stitle><addtitle>Qual Life Res</addtitle><date>2016-07-01</date><risdate>2016</risdate><volume>25</volume><issue>7</issue><spage>1743</spage><epage>1750</epage><pages>1743-1750</pages><issn>0962-9343</issn><eissn>1573-2649</eissn><abstract>Purpose To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People's Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. Results At baseline, mean age was 73.1 (range 65-90) and 62.0 % were women. Mean FI was 0.17 (range 0.00-0.66), and mean OPQOL was 130.80 (range 93-163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = —47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to -1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. Conclusions Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.</abstract><cop>Cham</cop><pub>Springer</pub><pmid>26747318</pmid><doi>10.1007/s11136-015-1213-2</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Activities of daily living Aged Aged, 80 and over CLINICAL AND POLICY APPLICATIONS Clinical trials Comorbidity Ethnic Groups Ethnicity Exercise Female Frail Elderly - statistics & numerical data Frailty Genotype & phenotype Geriatric Assessment Geriatrics Gerontology Humans Male Medicine Medicine & Public Health Older adults Older people Phenotypes Physical fitness Primary care Public Health Quality of Life Quality of Life Research Questionnaires Residence Characteristics - statistics & numerical data Sociology Surveys and Questionnaires United Kingdom Wellbeing |
| title | Frailty predicts trajectories of quality of life over time among British community-dwelling older people |
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