Expression of importin-α isoforms in human nasal mucosa: implication for adaptation of avian influenza A viruses to human host

Transportation into the host cell nucleus is crucial for replication and transcription of influenza virus. The classical nuclear import is regulated by specific cellular factor, importin-α. Seven isoforms of importin-α have been identified in human. The preference of importin-α3 of avian influenza v...

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