Pervasive polymorphic imprinted methylation in the human placenta

The maternal and paternal copies of the genome are both required for mammalian development, and this is primarily due to imprinted genes, those that are monoallelically expressed based on parent-of-origin. Typically, this pattern of expression is regulated by differentially methylated regions (DMRs)...

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Veröffentlicht in:	Genome research 2016-06, Vol.26 (6), p.756-767
Hauptverfasser:	Hanna, Courtney W, Peñaherrera, Maria S, Saadeh, Heba, Andrews, Simon, McFadden, Deborah E, Kelsey, Gavin, Robinson, Wendy P
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Methylation Female Genomic Imprinting Humans Male Placenta - physiology Polymorphism, Genetic Pregnancy Sequence Analysis, DNA
Online-Zugang:	Volltext
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