Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity

Poor bioavailability of Docetaxel (DCT) arising due to its low aqueous solubility and permeability limits its clinical utility. The aim of the present study was to develop DCT loaded self-emulsified drug delivery systems (D-SEDDS) and evaluate its potential ability to improve the oral bioavailabilit...

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Veröffentlicht in:Scientific reports 2016-05, Vol.6 (1), p.26895-26895, Article 26895
Hauptverfasser: Valicherla, Guru R., Dave, Kandarp M., Syed, Anees A., Riyazuddin, Mohammed, Gupta, Anand P., Singh, Akhilesh, Wahajuddin, Mitra, Kalyan, Datta, Dipak, Gayen, Jiaur R.
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Sprache:eng
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