Lack of Galanin 3 Receptor Aggravates Murine Autoimmune Arthritis

Neurogenic inflammation mediated by peptidergic sensory nerves has a crucial impact on the pathogenesis of various joint diseases. Galanin is a regulatory sensory neuropeptide, which has been shown to attenuate neurogenic inflammation, modulate neutrophil activation, and be involved in the developme...

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Veröffentlicht in:	Journal of molecular neuroscience 2016-06, Vol.59 (2), p.260-269
Hauptverfasser:	Botz, Bálint, Kemény, Ágnes, Brunner, Susanne M., Sternberg, Felix, Csepregi, Janka, Mócsai, Attila, Pintér, Erika, McDougall, Jason J., Kofler, Barbara, Helyes, Zsuzsanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory agents Arthritis Arthritis - genetics Arthritis - metabolism Arthritis - pathology Autoimmune Diseases - genetics Autoimmune Diseases - metabolism Autoimmune Diseases - pathology Biomedicine Capillary Permeability Cell activation Cell Biology Cell surface Edema Edema - metabolism Endothelium, Vascular - metabolism Fluorescence Galanin Hindlimb - pathology Hyperalgesia Immune system In vivo methods and tests Inflammation Joint diseases Joints (anatomy) Leukocytes (neutrophilic) Male Medical imaging Mice Neurochemistry Neurology Neurosciences Neutrophils Neutrophils - metabolism Pain perception Pathogenesis Proteomics Receptor, Galanin, Type 3 - deficiency Receptor, Galanin, Type 3 - genetics Receptors Sensory neurons
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