Phospholipase Cβ connects G protein signaling with RNA interference

Phosphoinositide-specific-phospholipase Cβ (PLCβ) is the main effector of Gαq stimulation which is coupled to receptors that bind acetylcholine, bradykinin, dopamine, angiotensin II as well as other hormones and neurotransmitters. Using a yeast two-hybrid and other approaches, we have recently found...

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Veröffentlicht in:	Advances in biological regulation 2016-05, Vol.61, p.51-57
Hauptverfasser:	Scarlata, Suzanne, Garwain, Osama, Williams, Leo, Burguera, Imanol Gonzalez, Rosati, Barbara, Sahu, Shriya, Guo, Yuanjian, Philip, Finly, Golebiewska, Urszula
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Binding, Competitive Calcium - metabolism Calcium signaling Cell Membrane - metabolism Component 3 promoter of RNA silencing Cytosol - metabolism G protein signaling GTP-Binding Protein alpha Subunits, Gq-G11 - genetics GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism HEK293 Cells Humans Phospholipase C beta - genetics Phospholipase C beta - metabolism Phospholipase Cβ Protein Binding RNA Interference RNA silencing RNA, Small Interfering - genetics RNA, Small Interfering - metabolism RNA-Induced Silencing Complex - genetics RNA-Induced Silencing Complex - metabolism Signal Transduction - genetics
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