Plasma from pre‐eclamptic patients induces the expression of the anti‐angiogenic miR‐195‐5p in endothelial cells

We examined the effect of plasma incubation from preeclampsia pregnant on the antiangiogenic miR‐195‐5p expression. Higher miR‐195‐5p expression was found in cultures incubated with preeclampsia plasma compared to those incubated with healthy pregnant plasma. Next, as VEGF is a target of miR‐195‐5p...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2016-06, Vol.20 (6), p.1198-1200
Hauptverfasser:	Sandrim, Valeria Cristina, Dias, Mayara Caldeira, Bovolato, Ana Lívia de Carvalho, Tanus‐Santos, Jose E, Deffune, Elenice, Cavalli, Ricardo C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Angiogenesis Angiogenesis Inhibitors - metabolism Antiangiogenics Cell culture Endothelial cells Enzyme-linked immunosorbent assay Female Gene expression Gene Expression Regulation Human Umbilical Vein Endothelial Cells - metabolism Humans HUVECs Kinases Liver cancer microRNA MicroRNAs - genetics MicroRNAs - metabolism miR‐195 Neovascularization, Physiologic Plasma Pre-eclampsia Pre-Eclampsia - blood Preeclampsia Pregnancy Proteins Short Communication Short Communications Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism VEGF
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