Single- and Repeated-Dose Pharmacokinetics of Ceftaroline in Plasma and Soft Tissues of Healthy Volunteers for Two Different Dosing Regimens of Ceftaroline Fosamil

Ceftaroline fosamil (CPT-F) is currently approved for use for the treatment of complicated skin and soft tissue infections and community-acquired pneumonia at 600 mg twice daily (q12h), but other dosing regimens are under evaluation. To date, very limited data on the soft tissue pharmacokinetics (PK...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 2016-06, Vol.60 (6), p.3617-3625
Hauptverfasser: Matzneller, Peter, Lackner, Edith, Lagler, Heimo, Wulkersdorfer, Beatrix, Österreicher, Zoe, Zeitlinger, Markus
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Sprache:eng
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