Management of atypical femoral fracture: a scoping review and comprehensive algorithm

Atypical femoral fractures (AFF) are a rare type of femoral stress fracture recently described, potentially associated with prolonged bisphosphonate therapy. Evidence-based recommendations regarding diagnosis and management of these fractures are scarce. The purpose of this study is to propose an al...

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Veröffentlicht in:BMC musculoskeletal disorders 2016-05, Vol.17 (223), p.227-227, Article 227
Hauptverfasser: Toro, Giuseppe, Ojeda-Thies, Cristina, Calabrò, Giampiero, Toro, Gabriella, Moretti, Antimo, Guerra, Guillermo Martínez-Díaz, Caba-Doussoux, Pedro, Iolascon, Giovanni
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Sprache:eng
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Zusammenfassung:Atypical femoral fractures (AFF) are a rare type of femoral stress fracture recently described, potentially associated with prolonged bisphosphonate therapy. Evidence-based recommendations regarding diagnosis and management of these fractures are scarce. The purpose of this study is to propose an algorithm for the diagnosis and management of AFF. We performed a PubMed search of the last ten years using the keywords "atypical femoral fractures" and identified further articles through an evaluation of the publications cited in these articles. Relevant studies were included by agreement between researchers, depending on their specialization. Pertinent points of debate were discussed based on the available literature, allowing for consensus regarding the proposed management algorithm. Using a systematic approach we performed a scoping review that included a total of 137 articles. A practical guide for diagnosis and management of AFF based on the current concepts is proposed. In spite of the impressive large volume of published literature available since AFF were initially identified, the level of evidence is mostly poor, in particular regarding treatment choice. Therefore, further studies are required.
ISSN:1471-2474
1471-2474
DOI:10.1186/s12891-016-1086-8