1,3-Propanediol binds inside the water-conducting pore of aquaporin 4: Does this efficacious inhibitor have sufficient potency?

Among the thirteen types of water channel proteins, aquaporins (AQPs), which play various essential roles in human physiology, AQP4 is richly expressed in cells of the central nervous system and implicated in pathological conditions such as brain edema. Therefore, researchers have been looking for w...

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Veröffentlicht in:	Journal of systems and integrative neuroscience 2016, Vol.2 (1), p.91-98
Hauptverfasser:	Yu, Lili, Villarreal, Oscar D, Chen, L Laurie, Chen, Liao Y
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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