Bayesian predictive modeling for genomic based personalized treatment selection

Efforts to personalize medicine in oncology have been limited by reductive characterizations of the intrinsically complex underlying biological phenomena. Future advances in personalized medicine will rely on molecular signatures that derive from synthesis of multifarious interdependent molecular qu...

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Veröffentlicht in:	Biometrics 2016-06, Vol.72 (2), p.575-583
Hauptverfasser:	Ma, Junsheng, Stingo, Francesco C., Hobbs, Brian P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Bayes Theorem Bayesian analysis Bayesian theory biological properties and phenomena BIOMETRIC PRACTICE biometry Biometry - methods Computer Simulation Data Interpretation, Statistical Diagnosis, Computer-Assisted Gene expression Gene Expression Profiling Generalized linear models genome Genomics Glioma - genetics Humans leukemia Leukemia - genetics linear models medicine Models, Statistical Partial exchangeability patients Personalized medicine Precision Medicine - methods Predictive probability quantitative analysis therapeutics Therapy, Computer-Assisted - statistics & numerical data Unsupervised clustering
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