Combinatorial biosynthesis of RiPPs: docking with marine life

•Observations from marine RiPP biosynthesis teaches us lessons about peptide combinatorial libraries.•Marine RiPP substrates contain mutable hypervariable cores, which are coupled with promiscuous posttranslational modification enzymes.•Marine RiPPs led to the discovery of conserved enzyme recogniti...

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Veröffentlicht in:	Current opinion in chemical biology 2016-04, Vol.31, p.15-21
Hauptverfasser:	Sardar, Debosmita, Schmidt, Eric W
Format:	Artikel
Sprache:	eng
Schlagworte:	Marine Biology Peptide Biosynthesis Peptide Library Protein Processing, Post-Translational
Online-Zugang:	Volltext
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