Gaze related enhancement of hemispheric blood flow in a stroke patient
OBJECTIVE: A patient with a right posterior cerebral artery territory infarction and a left superior quadrantanopia exhibited improvement on various visual tasks including Goldmann perimetry during extreme right gaze. The phenomenon was investigated by functional imaging of cerebral blood flow. METH...
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| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1997-05, Vol.62 (5), p.538-540 |
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| container_title | Journal of neurology, neurosurgery and psychiatry |
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| creator | Nadeau, S E Crosson, B Schwartz, R L Heilman, K M |
| description | OBJECTIVE: A patient with a right posterior cerebral artery territory infarction and a left superior quadrantanopia exhibited improvement on various visual tasks including Goldmann perimetry during extreme right gaze. The phenomenon was investigated by functional imaging of cerebral blood flow. METHODS: [(99m)Tc]HMPAO SPECT was carried out while the patient gazed to the right and to the left at an 8 Hz flash stimulus. RESULTS: When compared with left gaze, photic stimulation during right gaze was associated with an up to 39.8% increase in regional cerebral blood flow in the damaged right hemisphere, including Brodmann's areas 3-1-2, 7, 21, 22, 39, and 40. CONCLUSIONS: These gaze related alterations in function and synaptic activity suggest the engagement of a novel arousal-like mechanism that may account in part for comparable findings in patients with neglect and other disorders, and may have relevance to rehabilitation. |
| doi_str_mv | 10.1136/jnnp.62.5.538 |
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The phenomenon was investigated by functional imaging of cerebral blood flow. METHODS: [(99m)Tc]HMPAO SPECT was carried out while the patient gazed to the right and to the left at an 8 Hz flash stimulus. RESULTS: When compared with left gaze, photic stimulation during right gaze was associated with an up to 39.8% increase in regional cerebral blood flow in the damaged right hemisphere, including Brodmann's areas 3-1-2, 7, 21, 22, 39, and 40. CONCLUSIONS: These gaze related alterations in function and synaptic activity suggest the engagement of a novel arousal-like mechanism that may account in part for comparable findings in patients with neglect and other disorders, and may have relevance to rehabilitation.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.62.5.538</identifier><identifier>PMID: 9153619</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Biological and medical sciences ; Brain - blood supply ; Brain - diagnostic imaging ; Brain Ischemia - diagnosis ; Brain Ischemia - physiopathology ; Humans ; Male ; Medical sciences ; Middle Aged ; Neurology ; Occipital Lobe - physiopathology ; Photic Stimulation ; Regional Blood Flow ; Temporal Lobe - physiopathology ; Tomography, Emission-Computed, Single-Photon ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 1997-05, Vol.62 (5), p.538-540</ispartof><rights>1997 INIST-CNRS</rights><rights>Copyright BMJ Publishing Group LTD May 1997</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b509t-fa1a31b5410f6a1ce9f2ac47df1d2610482294c5f68697cdde6ff0402d5da1973</citedby><cites>FETCH-LOGICAL-b509t-fa1a31b5410f6a1ce9f2ac47df1d2610482294c5f68697cdde6ff0402d5da1973</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC486881/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC486881/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2688110$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9153619$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nadeau, S E</creatorcontrib><creatorcontrib>Crosson, B</creatorcontrib><creatorcontrib>Schwartz, R L</creatorcontrib><creatorcontrib>Heilman, K M</creatorcontrib><title>Gaze related enhancement of hemispheric blood flow in a stroke patient</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>OBJECTIVE: A patient with a right posterior cerebral artery territory infarction and a left superior quadrantanopia exhibited improvement on various visual tasks including Goldmann perimetry during extreme right gaze. The phenomenon was investigated by functional imaging of cerebral blood flow. METHODS: [(99m)Tc]HMPAO SPECT was carried out while the patient gazed to the right and to the left at an 8 Hz flash stimulus. RESULTS: When compared with left gaze, photic stimulation during right gaze was associated with an up to 39.8% increase in regional cerebral blood flow in the damaged right hemisphere, including Brodmann's areas 3-1-2, 7, 21, 22, 39, and 40. 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Crosson, B ; Schwartz, R L ; Heilman, K M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b509t-fa1a31b5410f6a1ce9f2ac47df1d2610482294c5f68697cdde6ff0402d5da1973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Biological and medical sciences</topic><topic>Brain - blood supply</topic><topic>Brain - diagnostic imaging</topic><topic>Brain Ischemia - diagnosis</topic><topic>Brain Ischemia - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Occipital Lobe - physiopathology</topic><topic>Photic Stimulation</topic><topic>Regional Blood Flow</topic><topic>Temporal Lobe - physiopathology</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nadeau, S E</creatorcontrib><creatorcontrib>Crosson, B</creatorcontrib><creatorcontrib>Schwartz, R L</creatorcontrib><creatorcontrib>Heilman, K M</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nadeau, S E</au><au>Crosson, B</au><au>Schwartz, R L</au><au>Heilman, K M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gaze related enhancement of hemispheric blood flow in a stroke patient</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>62</volume><issue>5</issue><spage>538</spage><epage>540</epage><pages>538-540</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>OBJECTIVE: A patient with a right posterior cerebral artery territory infarction and a left superior quadrantanopia exhibited improvement on various visual tasks including Goldmann perimetry during extreme right gaze. 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| ispartof | Journal of neurology, neurosurgery and psychiatry, 1997-05, Vol.62 (5), p.538-540 |
| issn | 0022-3050 1468-330X |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Brain - blood supply Brain - diagnostic imaging Brain Ischemia - diagnosis Brain Ischemia - physiopathology Humans Male Medical sciences Middle Aged Neurology Occipital Lobe - physiopathology Photic Stimulation Regional Blood Flow Temporal Lobe - physiopathology Tomography, Emission-Computed, Single-Photon Vascular diseases and vascular malformations of the nervous system |
| title | Gaze related enhancement of hemispheric blood flow in a stroke patient |
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