β-Adrenergic-mediated vasodilation in young men and women: cyclooxygenase restrains nitric oxide synthase

We tested the hypothesis that women exhibit greater vasodilator responses to β-adrenoceptor stimulation compared with men. We further hypothesized women exhibit a greater contribution of nitric oxide synthase and cyclooxygenase to β-adrenergic-mediated vasodilation compared with men. Forearm blood f...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2016-03, Vol.310 (6), p.H756-H764
Hauptverfasser:	Limberg, Jacqueline K, Johansson, Rebecca E, Peltonen, Garrett L, Harrell, John W, Kellawan, J Mikhail, Eldridge, Marlowe W, Sebranek, Joshua J, Schrage, William G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - pharmacology Adult Cyclooxygenase Inhibitors - pharmacology Enzyme Inhibitors - pharmacology Female Forearm - blood supply Humans Infusions, Intra-Arterial Integrative Cardiovascular Physiology and Pathophysiology Isoproterenol - pharmacology Ketorolac - pharmacology Male Microcirculation - drug effects Microcirculation - physiology Nitric Oxide Synthase - antagonists & inhibitors omega-N-Methylarginine - pharmacology Prostaglandin-Endoperoxide Synthases - physiology Sex Factors Ultrasonography, Doppler Vasodilation - drug effects Vasodilation - physiology
Online-Zugang:	Volltext
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