Repression of harmful meiotic recombination in centromeric regions

During the first division of meiosis, segregation of homologous chromosomes reduces the chromosome number by half. In most species, sister chromatid cohesion and reciprocal recombination (crossing-over) between homologous chromosomes are essential to provide tension to signal proper chromosome segre...

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Veröffentlicht in:	Seminars in cell & developmental biology 2016-06, Vol.54, p.188-197
Hauptverfasser:	Nambiar, Mridula, Smith, Gerald R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Animals Centromere - metabolism Centromeres Chromosome segregation Chromosome Segregation - genetics Crossing-over DNA Breaks, Double-Stranded Gene Conversion Homologous recombination Humans Meiosis Meiosis - genetics Recombination, Genetic
Online-Zugang:	Volltext
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