CXCR7 Mediates Neural Progenitor Cells Migration to CXCL12 Independent of CXCR4

Neural progenitor cell (NPC) migration is an essential process for brain development, adult neurogenesis, and neuroregeneration after brain injury. Stromal cell‐derived factor‐1 (SDF‐1, CXCL12) and its traditional receptor CXCR4 are well known to regulate NPC migration. However, the discovery of CXC...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2015-08, Vol.33 (8), p.2574-2585
Hauptverfasser:	Chen, Qiang, Zhang, Min, Li, Yuju, Xu, Dongsheng, Wang, Yi, Song, Aihong, Zhu, Bing, Huang, Yunlong, Zheng, Jialin C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell adhesion & migration Cell migration Cell signaling Chemokine CXCL12 - genetics Chemokine CXCL12 - metabolism Chemokine receptor Chemotaxis MAP Kinase Signaling System Mice Mice, Knockout Mitogen-Activated Protein Kinase 3 - genetics Mitogen-Activated Protein Kinase 3 - metabolism Neural stem cell Neural Stem Cells - cytology Neural Stem Cells - metabolism Neurogenesis Neuropeptides - genetics Neuropeptides - metabolism rac1 GTP-Binding Protein - genetics rac1 GTP-Binding Protein - metabolism Receptors, CXCR - genetics Receptors, CXCR - metabolism Receptors, CXCR4 - genetics Receptors, CXCR4 - metabolism
Online-Zugang:	Volltext
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