Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency

Background Common variable immunodeficiency (CVID) is an antibody deficiency treated with immunoglobulin; however, patients can have noninfectious inflammatory conditions that lead to heightened morbidity and mortality. Objectives Modular analyses of RNA transcripts in whole blood previously identif...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2016-04, Vol.137 (4), p.1206-1215.e6
Hauptverfasser:	Cols, Montserrat, PhD, Rahman, Adeeb, PhD, Maglione, Paul J., MD, PhD, Garcia-Carmona, Yolanda, PhD, Simchoni, Noa, PhD, Ko, Huai-Bin M., MD, Radigan, Lin, Cerutti, Andrea, MD, PhD, Blankenship, Derek, PhD, Pascual, Virginia, MD, Cunningham-Rundles, Charlotte, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Allergy and Immunology Antigens Biomarkers - metabolism Biopsy Common variable immunodeficiency Common Variable Immunodeficiency - immunology Common Variable Immunodeficiency - pathology Cytokines Cytokines - metabolism Enzyme-Linked Immunosorbent Assay Expansion Female Flow Cytometry Humans Immunoglobulins Infections Inflammation inflammatory complications Inflammatory diseases innate lymphoid cells Intestines - immunology Intestines - pathology Lung - immunology Lung - pathology Lung diseases Lymphocytes - immunology Lymphocytes - metabolism Male Middle Aged Mortality mucosal disease Real-Time Polymerase Chain Reaction Transcription factors Young Adult
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