Turning Bone Morphogenetic Protein 2 (BMP2) on and off in Mesenchymal Cells

The concentration, location, and timing of bone morphogenetic protein 2 (BMP2, HGNC:1069, GeneID: 650) gene expression must be precisely regulated. Abnormal BMP2 levels cause congenital anomalies and diseases involving the mesenchymal cells that differentiate into muscle, fat, cartilage, and bone. T...

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Veröffentlicht in:	Journal of cellular biochemistry 2015-10, Vol.116 (10), p.2127-2138
Hauptverfasser:	Rogers, Melissa B., Shah, Tapan A., Shaikh, Nadia N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis - genetics Bone Morphogenetic Protein 2 - biosynthesis Bone Morphogenetic Protein 2 - genetics CALCIFICATION Calcinosis - genetics Calcinosis - pathology Chondrogenesis - genetics Gene Expression Regulation GENE REGULATION GROWTH FACTOR Humans MESENCHYMAl CELL Mesoderm - cytology Mesoderm - metabolism Mesoderm - pathology MORPHOGEN Muscle Development - genetics Osteoarthritis - genetics Osteoarthritis - pathology Osteogenesis - genetics Osteoporosis - genetics Osteoporosis - pathology POST-TRANSCRIPTIONAL Regulatory Sequences, Nucleic Acid TRANSCRIPTION
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