Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation

A scalable and cost‐effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with defined commercial media is presented. This substrate can be applied to common cultureware and used off‐the‐shelf after lo...

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Veröffentlicht in:	Advanced materials (Weinheim) 2015-07, Vol.27 (27), p.4006-4012
Hauptverfasser:	Celiz, Adam D., Smith, James G. W., Patel, Asha K., Hook, Andrew L., Rajamohan, Divya, George, Vinoj T., Flatt, Luke, Patel, Minal J., Epa, Vidana C., Singh, Taranjit, Langer, Robert, Anderson, Daniel G., Allen, Nicholas D., Hay, David C., Winkler, David A., Barrett, David A., Davies, Martyn C., Young, Lorraine E., Denning, Chris, Alexander, Morgan R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Adhesion - physiology Cell Culture Techniques - instrumentation Cell Differentiation - physiology Cell Line Cell Lineage Communication Communications Culture Media Differentiation Fluorescent Antibody Technique high throughput High-Throughput Screening Assays Human human pluripotent stem cells Humans materials discovery Media Microarray Analysis Pluripotent Stem Cells - physiology polymer microarrays Polymers stem cell differentiation Stem cells
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