Mechanisms of Lung Fibrosis Resolution

Fibrogenesis involves a dynamic interplay between factors that promote the biosynthesis and deposition of extracellular matrix along with pathways that degrade the extracellular matrix and eliminate the primary effector cells. Opposing the often held perception that fibrotic tissue is permanent, ani...

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Veröffentlicht in:	The American journal of pathology 2016-05, Vol.186 (5), p.1066-1077
Hauptverfasser:	Glasser, Stephan W, Hagood, James S, Wong, Simon, Taype, Carmen A, Madala, Satish K, Hardie, William D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Collagen - physiology Enzymes - physiology Extracellular Matrix - metabolism Extracellular Matrix - physiology Humans Lysosomes - metabolism Mice Models, Animal Pathology Proteolysis Pulmonary Fibrosis - metabolism Pulmonary Fibrosis - physiopathology Review
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