Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin

The mucosal adjuvant activity of cholera toxin depends on the microbiota, which signals through Nod2 on CD11c + cells. Cholera toxin (CT) is a potent adjuvant for inducing mucosal immune responses. However, the mechanism by which CT induces adjuvant activity remains unclear. Here we show that the mi...

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