Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans

Homologous recombination (HR) repairs cytotoxic DNA double-strand breaks (DSBs) with high fidelity. Deficiencies in HR result in genome instability. A key early step in HR is the search for and invasion of a homologous DNA template by a single-stranded RAD-51 nucleoprotein filament. The Shu complex,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genetics (Austin) 2016-05, Vol.203 (1), p.133-145
Hauptverfasser:	McClendon, T Brooke, Sullivan, Meghan R, Bernstein, Kara A, Yanowitz, Judith L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - chemistry Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Carrier Proteins - metabolism Cell Line Chromosomes CRISPR-Cas Systems DNA damage Gene Expression Gene Order Genes Genetic Loci Germ-Line Mutation Homologous Recombination Investigations Multiprotein Complexes - metabolism Mutagens - toxicity Mutation Nematodes Protein Binding Protein Interaction Domains and Motifs Protein Interaction Mapping Rad51 Recombinase - genetics Rad51 Recombinase - metabolism Recombinational DNA Repair - drug effects Saccharomyces cerevisiae Studies Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!