The site of the bite: Leishmania interaction with macrophages, neutrophils and the extracellular matrix in the dermis

Leishmania spp., the causative agents of leishmaniasis, are intracellular parasites, transmitted to humans via the bite of their sand fly vectors. Once inoculated, the promastigotes are exposed to the dermis, which is composed of extracellular matrix (ECM), growth factors and its resident cells. Pro...

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Veröffentlicht in:	Parasites & vectors 2016-05, Vol.9 (263), p.264-264, Article 264
Hauptverfasser:	de Menezes, Juliana Perrone, Saraiva, Elvira M, da Rocha-Azevedo, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals dermis Development and progression Diptera drugs Extracellular matrix Extracellular Matrix - pathology growth factors Health aspects Humans Immune response Insect Bites and Stings - parasitology Leishmania Leishmania - physiology leishmaniasis macrophages Macrophages - physiology neutrophils Neutrophils - physiology Observations parasites Phlebotominae promastigotes Properties Psychodidae - physiology Review
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