Microfluidic emulation of mechanical circulatory support device shear-mediated platelet activation

Thrombosis of ventricular assist devices (VADs) compromises their performance, with associated risks of systemic embolization, stroke, pump stop and possible death. Anti-thrombotic (AT) drugs, utilized to limit thrombosis, are largely dosed empirically, with limited testing of their efficacy. Furthe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomedical microdevices 2015-12, Vol.17 (6), p.117-11, Article 117
Hauptverfasser:	Dimasi, Annalisa, Rasponi, Marco, Sheriff, Jawaad, Chiu, Wei-Che, Bluestein, Danny, Tran, Phat L., Slepian, Marvin J., Redaelli, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Blood Platelets - cytology Channels Computational Biology Devices Dynamical systems Dynamics Effectiveness Engineering Engineering Fluid Dynamics Equipment Design Feasibility Studies Heart-Assist Devices Humans Lab-On-A-Chip Devices Microfluidics Nanotechnology Platelet Activation Point-of-Care Systems Shear stress Stress, Mechanical Thrombosis - therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!