IGF‐1 Regulates Vertebral Bone Aging Through Sex‐Specific and Time‐Dependent Mechanisms

ABSTRACT Advanced aging is associated with increased risk of bone fracture, especially within the vertebrae, which exhibit significant reductions in trabecular bone structure. Aging is also associated with a reduction in circulating levels of insulin‐like growth factor (IGF‐1). Studies have suggeste...

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Veröffentlicht in:Journal of bone and mineral research 2016-02, Vol.31 (2), p.443-454
Hauptverfasser: Ashpole, Nicole M, Herron, Jacquelyn C, Mitschelen, Matthew C, Farley, Julie A, Logan, Sreemathi, Yan, Han, Ungvari, Zoltan, Hodges, Erik L, Csiszar, Anna, Ikeno, Yuji, Humphrey, Mary Beth, Sonntag, William E
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Sprache:eng
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