Combined mesenchymal stem cell transplantation and interleukin-1 receptor antagonism after partial hepatectomy

AIM: To study the therapeutic effects of mesenchymal stem cells(MSCs) and an interleukin-1 receptor antagonist(IL-1Ra) in acute liver failure. METHODS: Chinese experimental miniature swine(15 ± 3 kg, 5-8 mo) were obtained from the Laboratory Animal Centre of the Affiliated Drum Tower Hospital of Nan...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2016-04, Vol.22 (16), p.4120-4135
Hauptverfasser:	Sang, Jian-Feng, Shi, Xiao-Lei, Han, Bing, Huang, Xu, Huang, Tao, Ren, Hao-Zhen, Ding, Yi-Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antagonist Stem Apoptosis - drug effects Basic Study cell Cell Proliferation - drug effects Cell Survival - drug effects Cells, Cultured cells Interleukin-1 Cytokines - blood Disease Models, Animal failu Hepatectomy Inflammation Mediators - blood Interleukin 1 Receptor Antagonist Protein - pharmacology Ki-67 Antigen - metabolism liver Liver - diagnostic imaging Liver - drug effects Liver - metabolism Liver - surgery Liver Failure, Acute - blood Liver Failure, Acute - diagnosis Liver Failure, Acute - pathology Liver Failure, Acute - therapy Liver Function Tests Liver Regeneration - drug effects Mesenchymal Mesenchymal Stem Cell Transplantation NF-kappa B - metabolism Proto-Oncogene Proteins c-akt - metabolism receptor Signal Transduction - drug effects stem Swine Swine, Miniature Time Factors Tomography, X-Ray Computed transplantation Acute Ultrasonography
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