Clinically relevant behavioral endpoints in a recurrent nitroglycerin migraine model in rats

Background This research sought to further validate the rat nitroglycerin (NTG) migraine model by comparing the effects of single versus recurrent NTG episodes on behavioral endpoints that mirror ICHD-3 diagnostic criteria for migraine, and to determine if the altered behavioral endpoints are reduce...

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Veröffentlicht in:	Journal of headache and pain 2016-04, Vol.17 (1), p.40-40, Article 40
Hauptverfasser:	Sufka, Kenneth J., Staszko, Stephanie M., Johnson, Ainslee P., Davis, Morgan E., Davis, Rachel E., Smitherman, Todd A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Disease Models, Animal Internal Medicine Male Medicine Medicine & Public Health Migraine Migraine Disorders - chemically induced Migraine Disorders - diagnosis Migraine Disorders - drug therapy Motor Activity - drug effects Neurology Nitroglycerin Pain Medicine Photophobia - chemically induced Photophobia - diagnosis Photophobia - drug therapy Rats Research Article Rodents Serotonin 5-HT1 Receptor Agonists - pharmacology Serotonin 5-HT1 Receptor Agonists - therapeutic use Sumatriptan - pharmacology Sumatriptan - therapeutic use Treatment Outcome Vasodilator Agents
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